Understanding the microbial basis of body odor in pre-pubescent children and teenagers/Experiment 2
From BugSigDB
Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09
Subjects
- Location of subjects
- Philippines
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Skin of body Entire integument,Entire skin,Integument,Integumental organ,Pelt,Skin,Skin organ,Skin of body,skin of body
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Body odor measurement body odour measurement,Body odor measurement,body odor measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- child neck
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- teen neck
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Malodor is a phenotype that is well known to arise from specific interactions between host-derived odor precursors and the microbial metabolism that they support
- Group 0 sample size Number of subjects in the control (unexposed) group
- 15
- Group 1 sample size Number of subjects in the case (exposed) group
- 15
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Signature 1
Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09
Source: Figure S3, S4
Description: Significant microbial genera and species associated with teen neck VS child neck
Abundance in Group 1: increased abundance in teen neck
| NCBI | Quality Control | Links |
|---|---|---|
| Cutibacterium | ||
| Cutibacterium acnes | ||
| Malassezia | ||
| Malassezia globosa |
Revision editor(s): WikiWorks, ChiomaBlessing
Signature 2
Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09
Source: Figure S3, S4
Description: Significant microbial genera and species associated with teen neck VS child neck
Abundance in Group 1: decreased abundance in teen neck
| NCBI | Quality Control | Links |
|---|---|---|
| Staphylococcus | ||
| Staphylococcus hominis |
Revision editor(s): WikiWorks, ChiomaBlessing
