Gut microbiome and innate immune response patterns in IgE-associated eczema/Experiment 3

From BugSigDB


Reviewed Marked as Reviewed by Folakunmi on 2024-2-17

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): WikiWorks, Folakunmi

Subjects

Location of subjects
Australia
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Delivery method DeliveryMethod,Delivery method,delivery method
Group 0 name Corresponds to the control (unexposed) group for case-control studies
vaginally delivered infant
Group 1 name Corresponds to the case (exposed) group for case-control studies
caesarean delivered infant
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
infant born by caesarean section
Group 0 sample size Number of subjects in the control (unexposed) group
7
Group 1 sample size Number of subjects in the case (exposed) group
7

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V3-V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Roche454

Statistical Analysis

Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No

Alpha Diversity

Pielou Quantifies how equal the community is numerically
unchanged
Shannon Estimator of species richness and species evenness: more weight on species richness
unchanged

Signature 1

Reviewed Marked as Reviewed by Folakunmi on 2024-2-17

Curated date: 2021/01/10

Curator: Lucy Mellor

Revision editor(s): WikiWorks, Folakunmi

Source: Figure 1a, Text (Effects of delivery mode on gut microbiome establishment )

Description: Median relative abundances (%) of the most abundant phyla in vaginally delivered infants and caesarean delivered infants at 1 week

Abundance in Group 1: increased abundance in caesarean delivered infant

NCBI Quality ControlLinks
Pseudomonadota

Revision editor(s): WikiWorks, Folakunmi

Signature 2

Reviewed Marked as Reviewed by Folakunmi on 2024-2-17

Curated date: 2021/01/10

Curator: Lucy Mellor

Revision editor(s): WikiWorks, Folakunmi

Source: Figure 1a, Text (Effects of delivery mode on gut microbiome establishment )

Description: Median relative abundances (%) of the most abundant phyla in vaginally delivered infants and caesarean delivered infants at 1 week

Abundance in Group 1: decreased abundance in caesarean delivered infant

NCBI Quality ControlLinks
Bacteroidota

Revision editor(s): WikiWorks, Folakunmi