Integrated gut virome and bacteriome dynamics in COVID-19 patients/Experiment 3

From BugSigDB


Reviewed Marked as Reviewed by Atrayees on 2023-7-10

Curated date: 2021/07/02

Curator: Claregrieve1

Revision editor(s): Claregrieve1, WikiWorks, Victoria

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
COVID-19 2019 novel coronavirus,2019 novel coronavirus infection,2019-nCoV,2019-nCoV infection,beta-CoV,beta-CoVs,betacoronavirus,coronavirus disease 2019,SARS-coronavirus 2,SARS-CoV-2,severe acute respiratory syndrome coronavirus 2,severe acute respiratory syndrome coronavirus 2 infectious disease,β-coronavirus,β-CoV,β-CoVs,COVID-19,cOVID-19
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Mild COVID-19 patients
Group 1 name Corresponds to the case (exposed) group for case-control studies
Severe COVID-19 patients
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Patients with severe COVID-19
Group 0 sample size Number of subjects in the control (unexposed) group
3
Group 1 sample size Number of subjects in the case (exposed) group
3

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Reviewed Marked as Reviewed by Atrayees on 2023-7-10

Curated date: 2021/07/02

Curator: Claregrieve1

Revision editor(s): Claregrieve1

Source: Table 2

Description: Differential abundance of microbial taxa between mild and severe COVID-19 patients

Abundance in Group 1: increased abundance in Severe COVID-19 patients

NCBI Quality ControlLinks
Corynebacterium durum
Rothia mucilaginosa
Enterococcus faecium
Campylobacter gracilis
Corynebacterium glucuronolyticum
Rothia aeria
Alloscardovia omnicolens
Enterococcus avium
Enterococcus casseliflavus
Leuconostoc lactis
Weissella confusa
unclassified Delftia
Eikenella glucosivorans
Campylobacter concisus
Citrobacter freundii
Klebsiella aerogenes
Streptococcus infantis
Megasphaera micronuciformis

Revision editor(s): Claregrieve1

Signature 2

Reviewed Marked as Reviewed by Atrayees on 2023-7-10

Curated date: 2021/07/02

Curator: Claregrieve1

Revision editor(s): Claregrieve1

Source: Table 2

Description: Differential abundance of microbial taxa between mild and severe COVID-19 patients

Abundance in Group 1: decreased abundance in Severe COVID-19 patients

NCBI Quality ControlLinks
Agathobacter rectalis

Revision editor(s): Claregrieve1