Characterization of respiratory microbial dysbiosis in hospitalized COVID-19 patients/Experiment 1

Reviewed Marked as Reviewed by Fatima on 2022/04/20

Curated date: 2021/07/02

Curator: Claregrieve1

Revision editor(s): WikiWorks, Fatima, Claregrieve1, Peace Sandy

Host species Species from which microbiome was sampled. Contact us to have more species added.: Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology: Nasopharynx Nasenrachenraum,Epipharynx,Nasal part of pharynx,Pars nasalis pharyngis,Rhinopharynx,Nasopharynx,nasopharynx

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology: COVID-19 2019 novel coronavirus,2019 novel coronavirus infection,2019-nCoV,2019-nCoV infection,beta-CoV,beta-CoVs,betacoronavirus,coronavirus disease 2019,SARS-coronavirus 2,SARS-CoV-2,severe acute respiratory syndrome coronavirus 2,severe acute respiratory syndrome coronavirus 2 infectious disease,β-coronavirus,β-CoV,β-CoVs,COVID-19,cOVID-19

Group 0 name Corresponds to the control (unexposed) group for case-control studies: Mild COVID-19 patients

Group 1 name Corresponds to the case (exposed) group for case-control studies: Severe COVID-19 patients

Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group: COVID-19 infected patients admitted to the ICU and requiring mechanical ventilation

16S variable region One or more hypervariable region(s) of the bacterial 16S gene: Not specified

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance: DNBSEQ-T7

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).: relative abundances