The association between vaginal bacterial composition and miscarriage: a nested case-control study/Experiment 1

Reviewed Marked as Reviewed by Fatima on 2021/10/20

Curated date: 2021/10/14

Curator: Titas

Revision editor(s): Fatima, Titas, WikiWorks

Host species Species from which microbiome was sampled. Contact us to have more species added.: Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology: Posterior fornix of vagina Pars posterior fornicis vaginae,Posterior fornix,Posterior part of fornix of vagina,Posterior fornix of vagina,posterior fornix of vagina

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology: Spontaneous abortion Abortion, spontaneous,Spontaneous abortion,spontaneous abortion

Group 0 name Corresponds to the control (unexposed) group for case-control studies: Viable control pregnancy

Group 1 name Corresponds to the case (exposed) group for case-control studies: First or second-trimester miscarriage

16S variable region One or more hypervariable region(s) of the bacterial 16S gene: V1-V2

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance: Illumina

Significance threshold p-value or FDR threshold used for differential abundance testing (if any): 0.05

Matched on Factors on which subjects have been matched on in a case-control study: age, body mass index, gestational age

Inverse Simpson Modification of Simpsons index D as 1/D to obtain high values in datasets of high diversity and vice versa: increased

Reviewed Marked as Reviewed by Fatima on 2021/10/20

Curated date: 2021/10/14

Curator: Titas

Revision editor(s): Titas

Source: Figure 2A

Description:

Abundance in Group 1: decreased abundance in First or second-trimester miscarriage

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Lactobacillus sp.

Revision editor(s): Titas