The association between vaginal bacterial composition and miscarriage: a nested case-control study/Experiment 2

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Reviewed Marked as Reviewed by Fatima on 2021/10/20

Curated date: 2021/10/14

Curator: Titas

Revision editor(s): LGeistlinger, Titas, WikiWorks

Subjects

Location of subjects

United Kingdom

Host species Species from which microbiome was sampled. Contact us to have more species added.

Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology

Posterior fornix of vagina Pars posterior fornicis vaginae,Posterior fornix,Posterior part of fornix of vagina,Posterior fornix of vagina,posterior fornix of vagina

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology

Spontaneous abortion Abortion, spontaneous,Spontaneous abortion,spontaneous abortion

Group 0 name Corresponds to the control (unexposed) group for case-control studies

Viable control pregnancy

Group 1 name Corresponds to the case (exposed) group for case-control studies

First trimester miscarriage

Group 0 sample size Number of subjects in the control (unexposed) group

81

Group 1 sample size Number of subjects in the case (exposed) group

64

16S variable region One or more hypervariable region(s) of the bacterial 16S gene

Not specified

Signature 1

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Reviewed Marked as Reviewed by Fatima on 2021/10/20

Curated date: 2021/10/14

Curator: Titas

Revision editor(s): Titas

Source: 2D

Description:

Abundance in Group 1: decreased abundance in First trimester miscarriage

NCBI	Quality Control	Links
Lactobacillus sp.

Revision editor(s): Titas

Signature 2

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Reviewed Marked as Reviewed by Fatima on 2021/10/20

Curated date: 2021/10/14

Curator: Titas

Revision editor(s): Titas

Source: Figure 2D + interpretation

Description: Samples deplete of Lactobacillus spp. display increased richness and diversity and colonization by potential pathogens.

Abundance in Group 1: increased abundance in First trimester miscarriage

NCBI	Quality Control	Links
Prevotella sp.
Streptococcus
Peptoniphilus
Ureaplasma
Dialister

Revision editor(s): Titas