Sensitive Quantitative Analysis of the Meconium Bacterial Microbiota in Healthy Term Infants Born Vaginally or by Cesarean Section/Experiment 1

Reviewed Marked as Reviewed by Shaimaa Elsafoury on 2021/02/09

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): Shaimaa, WikiWorks

Host species Species from which microbiome was sampled (if applicable): Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology: Meconium Meconium

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology: cesarean section caesarean section,cesarean section

Group 0 name Corresponds to the control (unexposed) group for case-control studies: vaginal delivery
Group 1 name Corresponds to the case (exposed) group for case-control studies: C-section
Group 0 sample size Number of subjects in the control (unexposed) group: 134
Group 1 sample size Number of subjects in the case (exposed) group: 17
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any): No information about pre-delivey duration. 3 Vaginally-delivered infants have been exposed to antibiotics (birth to sampling)

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance: RT-qPCR

Significance threshold p-value or FDR threshold used for differential abundance testing (if any): 0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?: No