Distinct gut microbiota in southeastern African and northern European infants/Experiment 1

From BugSigDB


Reviewed Marked as Reviewed by Claregrieve1 on 2022/08/31

Curated date: 2022/07/13

Curator: Kaluifeanyi101

Revision editor(s): Kaluifeanyi101, Claregrieve1, Peace Sandy

Subjects

Location of subjects
Finland
Malawi
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Socioeconomic status class,Socioeconomic status,socioeconomic status,socioeconomic factors
Group 0 name Corresponds to the control (unexposed) group for case-control studies
High-Income country (Finland)
Group 1 name Corresponds to the case (exposed) group for case-control studies
Low-income country (Malawi)
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
44 healthy 6-month-old rural infants from Malawi
Group 0 sample size Number of subjects in the control (unexposed) group
31
Group 1 sample size Number of subjects in the case (exposed) group
44
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
6 months

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
RT-qPCR

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No


Signature 1

Reviewed Marked as Reviewed by Claregrieve1 on 2022/08/31

Curated date: 2022/07/13

Curator: Kaluifeanyi101

Revision editor(s): Kaluifeanyi101, Claregrieve1

Source: Table 2

Description: Differential microbial abundance between Finnish and Malawian infants

Abundance in Group 1: increased abundance in Low-income country (Malawi)

NCBI Quality ControlLinks
Bifidobacterium bifidum
Bifidobacterium longum
Bifidobacterium

Revision editor(s): Kaluifeanyi101, Claregrieve1

Signature 2

Reviewed Marked as Reviewed by Claregrieve1 on 2022/08/31

Curated date: 2022/07/13

Curator: Kaluifeanyi101

Revision editor(s): Kaluifeanyi101, Claregrieve1

Source: Table 2

Description: Differential microbial abundance between Finnish and Malawian infants

Abundance in Group 1: decreased abundance in Low-income country (Malawi)

NCBI Quality ControlLinks
Akkermansia muciniphila
Bifidobacterium adolescentis
Bifidobacterium catenulatum
Blautia coccoides
Clostridioides difficile
Clostridium perfringens
Staphylococcus aureus
[Clostridium] leptum

Revision editor(s): Kaluifeanyi101, Claregrieve1