The gut microbiota of Colombians differs from that of Americans, Europeans and Asians
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Quality control
- Retracted paper
- Contamination issues suspected
- Batch effect issues suspected
- Uncontrolled confounding suspected
- Results are suspect (various reasons)
- Tags applied
Experiment 1
Subjects
- Location of subjects
- Colombia
- Denmark
- France
- Japan
- South Korea
- Spain
- United States of America
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Ethnic group Ethnicity,race,Ethnic group,ethnic group
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- USA data
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Colombia data
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- 30 healthy Colombia adults of both genders from the general population living in Medellin, Colombia South America.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 13
- Group 1 sample size Number of subjects in the case (exposed) group
- 30
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 4 Months
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V1-V3
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Roche454
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- PERMANOVA
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
- age, waist circumference, sex
Signature 1
Source: Table 2
Description: Taxonomic composition of the gut microbiota in the different datasets.
Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.
Abundance in Group 1: increased abundance in Colombia data
| NCBI | Quality Control | Links |
|---|---|---|
| Bacillota |
Revision editor(s): Kaluifeanyi101, Peace Sandy
Signature 2
Source: Table 2
Description: Taxonomic composition of the gut microbiota in the different datasets.
Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.
Abundance in Group 1: decreased abundance in Colombia data
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroides |
Revision editor(s): Kaluifeanyi101, Peace Sandy
Experiment 2
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Ethnic group Ethnicity,race,Ethnic group,ethnic group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Europe data
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- The European dataset consisted of the subset of 13 healthy volunteers (three women and 10 men) among Spanish, French, and Danish inhabitants whose microbiomes were published by the MetaHIT Consortium
- Group 1 sample size Number of subjects in the case (exposed) group
- 13
Lab analysis
Statistical Analysis
- Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
- age, sex
Signature 2
Source: Table 2
Description: Taxonomic composition of the gut microbiota in the different datasets.
Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.
Abundance in Group 1: decreased abundance in Europe data
| NCBI | Quality Control | Links |
|---|---|---|
| Bacillota |
Revision editor(s): Kaluifeanyi101
Experiment 3
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- South Korea data
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- The Korean dataset consisted of 14 lean and four overweight individuals (six women and 12 men)
- Group 0 sample size Number of subjects in the control (unexposed) group
- 54
- Group 1 sample size Number of subjects in the case (exposed) group
- 14
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 4 months
Lab analysis
Statistical Analysis
- Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
- age, waist circumference, sex
Signature 2
Source: Table 2
Description: Taxonomic composition of the gut microbiota in the different datasets
Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.
Abundance in Group 1: decreased abundance in South Korea data
| NCBI | Quality Control | Links |
|---|---|---|
| Bacillota |
Revision editor(s): Kaluifeanyi101, Peace Sandy
Experiment 4
Subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Japan data
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- The Japanese dataset consisted of 454-generated V1 and V2 16S rDNA sequences of 10 lean and one overweight adult (six females and five males) that participated in an intervention with probiotics
- Group 1 sample size Number of subjects in the case (exposed) group
- 11
Lab analysis
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V1-V2
Statistical Analysis
Signature 1
Source: Table 2
Description: Taxonomic composition of the gut microbiota in the different datasets.
Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.
Abundance in Group 1: increased abundance in Japan data
| NCBI | Quality Control | Links |
|---|---|---|
| Actinomycetota |
Revision editor(s): Kaluifeanyi101
Signature 2
Source: Table 2
Description: Taxonomic composition of the gut microbiota in the different datasets
Data presented as average ± standard deviation; P-values from ANOVA testing differences among lean, overweight, and obese subjects. WC = waist circumference; NA = not available.
Abundance in Group 1: decreased abundance in Japan data
| NCBI | Quality Control | Links |
|---|---|---|
| Bacillota |
Revision editor(s): Kaluifeanyi101, Peace Sandy
