Gut microbiota dysbiosis and diarrhea in kidney transplant recipients/Experiment 6

From BugSigDB


Reviewed Marked as Reviewed by Atrayees on 2023-6-7

Curated date: 2023/06/07

Curator: Atrayees

Revision editor(s): Atrayees, Victoria

Subjects

Location of subjects
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Diarrhea Diarrhea,Diarrhoea,Watery stool,diarrhea
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Pre-Diarrheal specimens
Group 1 name Corresponds to the case (exposed) group for case-control studies
Diarrheal specimens
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Diarrheal specimens
Group 0 sample size Number of subjects in the control (unexposed) group
14
Group 1 sample size Number of subjects in the case (exposed) group
14

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4-V5
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.15
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Reviewed Marked as Reviewed by Atrayees on 2023-6-7

Curated date: 2023/06/07

Curator: Atrayees

Revision editor(s): Atrayees

Source: Table S7

Description: Relative abundance of taxa in Diarrheal specimens

Abundance in Group 1: decreased abundance in Diarrheal specimens

NCBI Quality ControlLinks
Gemmiger
Ruminococcus
Eubacterium
Anaerostipes
Thomasclavelia
Coprobacillus
Oscillibacter
Ruminiclostridium
Bifidobacterium
Coprococcus
Escherichia
Bacteroides
Dorea

Revision editor(s): Atrayees

Signature 2

Reviewed Marked as Reviewed by Atrayees on 2023-6-7

Curated date: 2023/06/07

Curator: Atrayees

Revision editor(s): Atrayees

Source: Table S7

Description: Relative abundance of taxa in Diarrheal specimens

Abundance in Group 1: increased abundance in Diarrheal specimens

NCBI Quality ControlLinks
Streptococcus
Lachnoclostridium

Revision editor(s): Atrayees