Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2024-6-27
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Chronic inflammatory demyelinating polyradiculoneuropathy chronic inflammatory demyelinating polyradiculoneuropathy,chronic inflammatory demyelinating polyradiculoneuropathy (disorder),chronic relapsing polyneuropathy,CIDP,Polyradiculoneuropathy, Chronic Inflammatory Demyelinating,Chronic inflammatory demyelinating polyradiculoneuropathy
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Healthy controls (non-CIDP)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), a rare acquired immune-mediated neuropathy
- Group 0 sample size Number of subjects in the control (unexposed) group
- 33
- Group 1 sample size Number of subjects in the case (exposed) group
- 31
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- None
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- DNBSEQ-T7
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- T-Test
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- Matched on Factors on which subjects have been matched on in a case-control study
- age, sex
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2024-6-27
Source: Fig. 6A
Description: Bacterial species abundance in the stools of the chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) group versus non-CIDP group.
Abundance in Group 1: increased abundance in Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
Revision editor(s): Zheeburg, Scholastica
Signature 2
Reviewed Marked as Reviewed by Svetlana up on 2024-6-27
Source: Fig. 6A
Description: Bacterial species abundance in the stools of the chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) group versus non-CIDP group.
Abundance in Group 1: decreased abundance in Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
Revision editor(s): Zheeburg, Scholastica
