Specific gastrointestinal microbiota profiles in Chinese Tan sheep are associated with lauric acid content in muscle/Experiment 1

From BugSigDB


Needs review

Curated date: 2024/04/11

Curator: Scholastica

Revision editor(s): Scholastica

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Ovis aries
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Rumen Paunch,Rumen,rumen
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Gut microbiome measurement Gut microbiome measurement,gut microbiome measurement
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Rumen of Dorper sheep (D_R)
Group 1 name Corresponds to the case (exposed) group for case-control studies
Rumen of Tan Sheep (T_R)
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Rumen of Tan sheep bred in Ningxia, China
Group 0 sample size Number of subjects in the control (unexposed) group
4
Group 1 sample size Number of subjects in the case (exposed) group
4
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
No antibiotics during the experiment period

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Needs review

Curated date: 2024/04/11

Curator: Scholastica

Revision editor(s): Scholastica

Source: Fig. 3A

Description: A LEfSe Analysis of differences in rumen microbial composition among two sheep breeds from metagenomic data at the species level.

Abundance in Group 1: increased abundance in Rumen of Tan Sheep (T_R)

NCBI Quality ControlLinks
Faecalibacterium prausnitzii
Oscillibacter sp. PEA192
Stutzerimonas stutzeri
Stenotrophomonas maltophilia
Flavonifractor plautii
Mageeibacillus indolicus
Achromobacter xylosoxidans

Revision editor(s): Scholastica

Signature 2

Needs review

Curated date: 2024/04/11

Curator: Scholastica

Revision editor(s): Scholastica

Source: Fig. 3A

Description: A LEfSe Analysis of differences in rumen microbial composition among two sheep breeds from metagenomic data at the species level.

Abundance in Group 1: decreased abundance in Rumen of Tan Sheep (T_R)

NCBI Quality ControlLinks
Methanobrevibacter millerae
Methanosphaera sp. BMS

Revision editor(s): Scholastica