Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host/Experiment 9
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2024-7-15
Subjects
- Location of subjects
- Germany
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Sus scrofa domesticus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Jejunum Intestinum jejunum,Mid-intestine,Middle intestine,Jejunum,jejunum
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Gut microbiome measurement Gut microbiome measurement,gut microbiome measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Host (Ascaris suum infected Pigs) Microbiome
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Parasite (Ascaris suum) Microbiome
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Microbiome of intestines harvested from female adult Ascaris worms that were harvested from host's (pig) gut
- Group 0 sample size Number of subjects in the control (unexposed) group
- 10
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- raw counts
- Statistical test
- DESeq2
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Alpha Diversity
- Chao1 Abundance-based estimator of species richness
- decreased
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2024-7-15
Source: Figure 5A, Table S8
Description: Differentially abundant bacteria taxa in Host (Pig) versus Parasite (Ascaris suum) Microbiome
Abundance in Group 1: increased abundance in Parasite (Ascaris suum) Microbiome
Revision editor(s): Barrakat, Scholastica
Signature 2
Reviewed Marked as Reviewed by Svetlana up on 2024-7-15
Source: Figure 5A, Table S8
Description: Differentially abundant bacteria taxa in Host (Pig) versus Parasite (Ascaris suum) Microbiome
Abundance in Group 1: decreased abundance in Parasite (Ascaris suum) Microbiome
Revision editor(s): Barrakat, Scholastica
