Effects of removing in-feed antibiotics and zinc oxide on the taxonomy and functionality of the microbiota in post weaning pigs/Experiment 10

From BugSigDB


Needs review

Curated date: 2024/04/22

Curator: Fiddyhamma

Revision editor(s): Fiddyhamma

Subjects

Location of subjects
Ireland
Host species Species from which microbiome was sampled. Contact us to have more species added.
Sus scrofa domesticus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Abnormal sample abnormal tissue sample,altered sample,Abnormal sample,abnormal sample
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Faecal_0dpw AB(antibiotics) group
Group 1 name Corresponds to the case (exposed) group for case-control studies
Diarrhoea_0dpw AB(antibiotics) group
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Diarrhoea samples collected at day 0 post weaning from piglets treated with antibiotics

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Needs review

Curated date: 2024/04/22

Curator: Fiddyhamma

Revision editor(s): Fiddyhamma

Source: Suppl fig 3A and text

Description: Species associated with each dietary treatment in the analysis of Faecal_0dpw species data, according to LEfSe(Linear discriminant analysis Effect Size), most likely explaining the differences among dietary treatments.

Abundance in Group 1: decreased abundance in Diarrhoea_0dpw AB(antibiotics) group

NCBI Quality ControlLinks
Phocaeicola salanitronis

Revision editor(s): Fiddyhamma