Effects of removing in-feed antibiotics and zinc oxide on the taxonomy and functionality of the microbiota in post weaning pigs/Experiment 13

From BugSigDB


Needs review

Curated date: 2024/04/27

Curator: Fiddyhamma

Revision editor(s): Fiddyhamma

Subjects

Location of subjects
Ireland
Host species Species from which microbiome was sampled. Contact us to have more species added.
Sus scrofa domesticus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Abnormal sample abnormal tissue sample,altered sample,Abnormal sample,abnormal sample
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Faecal_14dpw Zn(Zinc Oxide) group
Group 1 name Corresponds to the case (exposed) group for case-control studies
Diarrhoea_14dpw Zn(Zinc Oxide) group
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Diarrhoea samples collected at day 14 post weaning from piglets treated with Zinc Oxide

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2


Signature 1

Needs review

Curated date: 2024/04/27

Curator: Fiddyhamma

Revision editor(s): Fiddyhamma

Source: Fig 5D, Suppl fig 4 and text

Description: Description: Description: Taxa associated with each dietary treatment in the analysis of Faecal_14dpw data. Significant species are coloured according to the treatment to which they are associated to, and are annotated in the cladogram as letters, which can be identified below it.

Abundance in Group 1: decreased abundance in Diarrhoea_14dpw Zn(Zinc Oxide) group

NCBI Quality ControlLinks
Bacteroidaceae
Bacteroides caccae
Bacteroides caecimuris
Bacteroides cellulosilyticus
Bacteroides fragilis
Bacteroides helcogenes
Bacteroides heparinolyticus
Bacteroides thetaiotaomicron
Thermoplasmatota
Clostridioides difficile
Draconibacterium orientale
Fermentimonas caenicola
Marinilabiliales
Methanomassiliicoccales
Methanomethylophilaceae
Methanomethylophilus alvi
Ornithobacterium rhinotracheale
Paludibacter propionicigenes
Paludibacteraceae
Parabacteroides distasonis
Phascolarctobacterium faecium
Phocaeicola salanitronis
Prolixibacteraceae
Tannerella forsythia
Tannerella serpentiformis
Tannerellaceae

Revision editor(s): Fiddyhamma