Discuss Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models

Note 1

The family Clostridiaceae was listed twice for increased in abundance in the TAC group when compared to TAC-CH.

Mogibacteriaceae is currently called Anaerovoracaceae.

The S24-7 bacteria is Muribaculaceae.

Note 2

The reason I did not add any experiments for F2-Generation is:

1. There were no differences in alpha diversity (data not shown) between groups, and family-level relative abundance was similar in both lineages.
2. The study also stated that "In this proof-of-concept study, we have demonstrated that variation in microbiota is negligible in F2-generation littermate mice generated from two C57BL/6 (WT) parental lineages"

Additionally, all the data that show differential abundance remained unchanged for both F2 mJAX and F2 mTAC, therefore showing no variation among them.