Discuss Gut microbiomes of agropastoral children from the Adadle region of Ethiopia reflect their unique dietary habits

Family XI

This taxon is found in the signatures of Experiments 1 & 2. Supplementary information 3 lists it under class Clostridia, order Peptostreptococcales-Tissierellales. There is no NCBI match for Peptostreptococcales-Tissierellalesthis, instead NCBI points to Clostridium cluster XI being synonym to Peptostreptococcaceae. Upon further inspection of Supplementary Information 3, there are several species listed under Family XI, most of which belong to Peptoniphilaceae, one to Eubacteriales incertae sedis. This makes the use of Peptostreptococcaceae uncertain. I decided to keep Clostridia Family XI.

Vagococcaceae

This family was changed to Enterococcaceae, based on https://lpsn.dsmz.de/family/enterococcaceae

candidate division VadinBE97

This taxa was originally recorded on the LEfSe graph as vadinBE97. Supplementary information 3 listed it under the following taxonomic classification: Verrucomicrobiota, Lentisphaeria, Victivallales, vadinBE97. NCBI classifies Lentisphaeria (Taxonomy ID: 1313211) as a class which contains candidate division VadinBE97.

Genus sp. C sp1/sp2 format

This format was used on several species in the Boxplot graphs for experiment 6, i.e. Streptococcus sp.C equinus/infantarius/lutetiensis. In Supplementary information 3, they are recorded with brackets (i.e. Streptococcus sp. [C equinus/infantarius/lutetiensis]) and have a NCBI ID (i.e. 1301) that is for the genus. The bracket and "C" seemed to suggest uncertain placement or a taxonomic complex. I matched some as subspecies and others as species noting the brackets content in the review bubble.

Experiments 11 and 12

The description on the graph specifies this is a heatmap for genera, however these list species, so I used species for the description of the signatures.

Prevotella 9 copri

Prevotella copri is the homotypic synonym for Segatella copri, however I didn't change it due to the 9 after the genus.

Figure 3D

This graph is curatable, its focus is on bacteria families that belong to the VANISH/BloSSUM categories, however, I did not curate it because signatures would repeat experiments 1-5 with less families..