Discuss Effects of proton pump inhibitor on the human gut microbiome profile in multi-ethnic groups in Singapore

The taxa of Proteobacteria phylum, Gammaproteobacteria class, Enterobacteriales order and Enterobacteriaceae family were only associated with the Day 7 group when it was compared to the Day 14 group, but not when the Day 7 group was compared to that from Day 1 (data not shown).

There was a significant increase in the relative abundance of the Bacilli class, Lactobacillales order, Streptococcaceae family, Streptococcus and Veillonella genera and Streptococcus vestibularis and Veillonella dispar species immediately after PPI use (Day 7), which diminished seven days after stopping omeprazole on Day 14.

Bacteroidetes phylum was associated with the Day 14 group when findings from that day were compared to those from Day 1 and Day 7 (data not shown).