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BugSigDB

A Comprehensive Database of Published Microbial Signatures

BugSigDB.org (published in Nature Biotechnology) is a community-editable Semantic Mediawiki knowledge management system. Its primary functions include 1. standardization of key elements of published microbiome studies using ontologies and the NCBI taxonomy, 2. searchability, 3. Enrichment Analysis using bulk exports, GMT files, or other software (e.g. bugsigdbr), and 4. community interaction: you can request an account, contribute or analyze, learn about the project, report issues, and ask questions on the #bugsigdb channel of the community-bioc Slack team. This collaborative effort aims to accelerate microbiome research by providing a comprehensive database of microbial signatures from published studies, along with relevant information on study design and geography, health outcomes, host body site, and experimental methods.

About this project

1301Featured Taxon

Streptococcus(genus)

cellular organismsBacteriaTerrabacteria groupBacillotaBacilliLactobacillalesStreptococcaceae

BugSigDB Statistics

• Number of studies: 280 (filter)
• Number of signatures: 477
• Number of direct descendants: 72

Study by nameFeatured Studies

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment
Oncotarget, 2016 | Saliva | Oral squamous cell carcinoma | United States of America

Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder
Journal of affective disorders, 2016 | Feces | Unipolar depression | Japan

Taxa

Filter signatures

Fuzzy | Parameterized | Logical operators » ExampleAdvanced Search

Statistics

• 1158 studies
• 5490 signatures
• 1467 unique taxa
• 30 host species
• 80 locations
• 165 body sites
• 414 conditions
• contributed by 172 contributors

Browse all studies by Host species | Body site | Condition | Taxa | Location of subjects.

Top 5 Contributors in the last 30 days

Last 30 days (Top 5)

Rank Score Pages Changes Username 1 117 117 117 Svetlana up 2 73 59 109 Aleru Divine 3 66 55 86 Rahila 4 38 21 91 KateRasheed 5 37 28 50 Fiddyhamma

Extended Statistics