Dietary Supplementation With Leucine or in Combination With Arginine Decreases Body Fat Weight and Alters Gut Microbiota Composition in Finishing Pigs/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by KateRasheed on 2025-6-6
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Sus scrofa domesticus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Colon Hindgut,Large bowel,Posterior intestine,Colon,colon
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Diet measurement Diet measurement,diet measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Combination of Leu_Glu (1.00% Leucine + 1.00% Glutamic acid), Leu_Arg ( 1.00% Leucine + 1.00% Arginine) and BD (basal diet)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Leu (Leucine) group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Pigs fed a basal diet supplemented with 1.00% Leucine + 1.37% alanine (Leu group)
- Group 0 sample size Number of subjects in the control (unexposed) group
- 36
- Group 1 sample size Number of subjects in the case (exposed) group
- 12
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Kruskall-Wallis
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Signature 1
Reviewed Marked as Reviewed by KateRasheed on 2025-6-6
Source: Figure 8A and 8B
Description: Taxonomic differences of colonic microbiota among the four groups. Comparison of relative abundance at the phylum (A) and genus (B) levels between the four groups.
Abundance in Group 1: increased abundance in Leu (Leucine) group
NCBI | Quality Control | Links |
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Actinomycetota | ||
Collinsella | ||
Coriobacteriaceae | ||
Slackia |
Revision editor(s): Tosin