Overabundance of Asaia and Serratia Bacteria Is Associated with Deltamethrin Insecticide Susceptibility in Anopheles coluzzii from Agboville, Côte d'Ivoire/Experiment 3
From BugSigDB
Needs review
Subjects
- Location of subjects
- Côte d'Ivoire
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Anopheles coluzzii
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Blood vessel Region of vascular tree organ,Vas sanguineum,Vascular element,Vascular tree organ region,Blood vessel,blood vessel
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Insecticide insecticides,Insecticide,insecticide
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Susceptible + Resistant mosquitoes (2 to 3 days old)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Control mosquitoes (2 to 3 days old)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Control mosquitoes refers to mosquitoes that were unexposed to insecticide (comprising a mix of age-matched individuals of unknown phenotype). They are mosquitoes from control bottle which were alive 60 minutes after the initiation of bioassay
- Group 0 sample size Number of subjects in the control (unexposed) group
- 138
- Group 1 sample size Number of subjects in the case (exposed) group
- 42
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- centered log-ratio
- Statistical test
- ANCOM
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Matched on Factors on which subjects have been matched on in a case-control study
- age
Signature 1
Needs review
Source: In text of the "Serratia and Asaia dominated in older and younger susceptible An. coluzzii." section and Fig. S5
Description: Differential abundance of taxa between susceptible, resistant and control mosquitoes using ANCOM
Abundance in Group 1: increased abundance in Control mosquitoes (2 to 3 days old)
| NCBI | Quality Control | Links |
|---|---|---|
| Enterobacteriaceae | ||
| Ochrobactrum | ||
| Lysinibacillus |
Revision editor(s): KateRasheed
