Overabundance of Asaia and Serratia Bacteria Is Associated with Deltamethrin Insecticide Susceptibility in Anopheles coluzzii from Agboville, Côte d'Ivoire/Experiment 4
From BugSigDB
Needs review
Subjects
- Location of subjects
- Côte d'Ivoire
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Anopheles coluzzii
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Blood vessel Region of vascular tree organ,Vas sanguineum,Vascular element,Vascular tree organ region,Blood vessel,blood vessel
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Insecticide insecticides,Insecticide,insecticide
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Control mosquitoes (2 to 3 days old)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Susceptible mosquitoes (2 to 3 days old)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Susceptible mosquitoes refers to the mosquitoes knocked down after exposure to 1× deltamethrin
- Group 0 sample size Number of subjects in the control (unexposed) group
- 42
- Group 1 sample size Number of subjects in the case (exposed) group
- 87
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- log transformation
- Statistical test
- Linear Regression
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Matched on Factors on which subjects have been matched on in a case-control study
- age
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- decreased
- Faith Phylogenetic diversity, takes into account phylogenetic distance of all taxa identified in a sample
- decreased
Signature 1
Needs review
Source: Table S5
Description: Differential abundance of taxa present in 2-3 day old Anopheles coluzzii (susceptible and control mosquitoes), as computed by Songbird.
Abundance in Group 1: increased abundance in Susceptible mosquitoes (2 to 3 days old)
Revision editor(s): KateRasheed
Signature 2
Needs review
Source: Table S5
Description: Differential abundance of taxa present in 2-3 day old Anopheles coluzzii (susceptible and control mosquitoes), as computed by Songbird.
Abundance in Group 1: decreased abundance in Susceptible mosquitoes (2 to 3 days old)
Revision editor(s): KateRasheed
