A cross-sectional analysis about bacterial vaginosis, high-risk human papillomavirus infection, and cervical intraepithelial neoplasia in Chinese women/Experiment 6

Reviewed Marked as Reviewed by Svetlana up on 2024-5-18

Curated date: 2024/04/23

Curator: Joan Chuks

Revision editor(s): Joan Chuks, Taofeecoh, WikiWorks

Host species Species from which microbiome was sampled. Contact us to have more species added.: Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology: Uterine cervix, Vaginal fluidUterine cervix,Vaginal fluid

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology: Human papilloma virus infection, Cervical intraepithelial neoplasia Human papilloma virus infection,Cervical Dysplasia,Cervical Intraepithelial Neoplasia,Cervical intraepithelial neoplasia,Cervical Intraepithelial Neoplasm,Cervical Intraepithelial Neoplasms,Cervix Intraepithelial Neoplasia,Cervix Uteri Intraepithelial Neoplasia,Intraepithelial Neoplasia of Cervix,Intraepithelial Neoplasia of Cervix Uteri,Intraepithelial Neoplasia of the Cervix,Intraepithelial Neoplasia of the Cervix Uteri,Intraepithelial Neoplasia of the Uterine Cervix,Intraepithelial Neoplasia of Uterine Cervix,Intraepithelial Neoplasia, Cervical,Intraepithelial Neoplasm, Cervical,Intraepithelial Neoplasms, Cervical,NEOPL CERVICAL INTRAEPITHELIAL,Neoplasia, Cervical Intraepithelial,Neoplasm, Cervical Intraepithelial,Neoplasms, Cervical Intraepithelial,Uterine Cervix Intraepithelial Neoplasia,cervical intraepithelial neoplasia

Group 0 name Corresponds to the control (unexposed) group for case-control studies: Bacterial Vaginosis (BV) Infected Women

Group 1 name Corresponds to the case (exposed) group for case-control studies: High‑risk human papillomavirus(HR-HPV) & Cervical Intraepithelial Neoplasia(CIN) co-infected women (HC)

Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group: Women attending the Aviation General hospital, located in Beijing, China, who were diagnosed with infection of High‑risk human papillomavirus (HR-HPV) combined with Cervical Intraepithelial Neoplasia (CIN).

Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any): 1 month

16S variable region One or more hypervariable region(s) of the bacterial 16S gene: V3-V4

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance: Illumina

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).: relative abundances