The human gut microbiota and glucose metabolism: a scoping review of key bacteria and the potential role of SCFAs/Experiment 3

From BugSigDB


Reviewed Marked as Reviewed by Svetlana up on 2025-3-6

Curated date: 2025/02/03

Curator: Aleru Divine

Revision editor(s): Aleru Divine, WikiWorks

Subjects

Location of subjects
Australia
Brazil
China
Denmark
Finland
France
Ghana
Greece
India
Iran
Ireland
Israel
Jamaica
Japan
Mexico
Poland
South Africa
South Korea
Spain
Sweden
United Kingdom
United States of America
Taiwan
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fÀkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Glucose C6H12O6,DL-glucose,Glc,gluco-hexose,Glucose,glucose,Glukose
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Bacteria associated with glucose metabolism outcomes
Group 1 name Corresponds to the case (exposed) group for case-control studies
Bacteria associated with glucose metabolism outcomes
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Relationship between the human gut microbiota and glucose metabolism, adjusted for metabolic drugs.
Group 0 sample size Number of subjects in the control (unexposed) group
45
Group 1 sample size Number of subjects in the case (exposed) group
45
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified

Statistical Analysis

MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes
Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
Confounders controlled for: "antidiabetic drugs" is not in the list (abnormal glucose tolerance, acetaldehyde, acute graft vs. host disease, acute lymphoblastic leukemia, acute myeloid leukemia, adenoma, age, AIDS, alcohol consumption measurement, alcohol drinking, ...) of allowed values.antidiabetic drugs, Confounders controlled for: "blood pressure lowering drugs" is not in the list (abnormal glucose tolerance, acetaldehyde, acute graft vs. host disease, acute lymphoblastic leukemia, acute myeloid leukemia, adenoma, age, AIDS, alcohol consumption measurement, alcohol drinking, ...) of allowed values.blood pressure lowering drugs, Confounders controlled for: "blood lipids lowering drugs" is not in the list (abnormal glucose tolerance, acetaldehyde, acute graft vs. host disease, acute lymphoblastic leukemia, acute myeloid leukemia, adenoma, age, AIDS, alcohol consumption measurement, alcohol drinking, ...) of allowed values.blood lipids lowering drugs


Signature 1

Reviewed Marked as Reviewed by Svetlana up on 2025-3-6

Curated date: 2025/02/03

Curator: Aleru Divine

Revision editor(s): Aleru Divine, WikiWorks

Source: Table 1

Description: Summary of reported associations between bacteria on different taxonomic levels and glucose-related outcomes adjusted for metabolic drugs.

Abundance in Group 1: increased abundance in Bacteria associated with glucose metabolism outcomes

NCBI Quality ControlLinks
Bacillota   
Synergistota   
Eubacteriales   
Lachnospiraceae   
Oscillospiraceae   
Bacteroides   
Blautia   
Clostridium   
Dorea   
Faecalibacterium   
Lactobacillus   
Megasphaera   
Prevotella   
Slackia   
Streptococcus   
Blautia obeum   
Blautia wexlerae   
Escherichia coli   
Enterocloster bolteae   
Faecalibacterium prausnitzii   
Megasphaera elsdenii   
Mediterraneibacter gnavus   

Revision editor(s): Aleru Divine, WikiWorks

Signature 2

Reviewed Marked as Reviewed by Svetlana up on 2025-3-6

Curated date: 2025/02/03

Curator: Aleru Divine

Revision editor(s): Aleru Divine, WikiWorks

Source: Table 1

Description: Summary of reported associations between bacteria on different taxonomic levels and glucose-related outcomes adjusted for metabolic drugs.

Abundance in Group 1: decreased abundance in Bacteria associated with glucose metabolism outcomes

NCBI Quality ControlLinks
Bacillota   
Eubacteriales   
Christensenellaceae   
Lachnospiraceae   
Oscillospiraceae   
Akkermansia   
Bacteroides   
Blautia   
Clostridium   
Faecalibacterium   
Prevotella   
Ruminococcus   
Akkermansia muciniphila   
Bifidobacterium longum   
Blautia coccoides   
Blautia obeum   
[Clostridium] leptum   
Dialister invisus   
Faecalibacterium prausnitzii   
Intestinibacter bartlettii   

Revision editor(s): Aleru Divine, WikiWorks