Multi-angle meta-analysis of the gut microbiome in Autism Spectrum Disorder: a step toward understanding patient subgroups/Experiment 4
From BugSigDB
Subjects
- Location of subjects
- Canada
- China
- India
- Italy
- United States of America
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Autism spectrum disorder atypical autism,autism spectrum disease,autism spectrum disorder,Autism Spectrum Disorders,autistic spectrum disorder,CHILD DEVELOPMENT DIS PERVASIVE,Child Development Disorders, Pervasive,Development Disorder, Pervasive,Development Disorders, Pervasive,Disorder, Autism Spectrum,Disorder, Pervasive Development,Disorders, Autism Spectrum,Disorders, Pervasive Development,PDD,PERVASIVE CHILD DEVELOPMENT DIS,Pervasive Child Development Disorders,Pervasive Development Disorder,Pervasive Development Disorders,pervasive developmental disorder - not otherwise specified,pervasive developmental disorders,Spectrum Disorder, Autism,Spectrum Disorders, Autism,Autism spectrum disorder
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- autism spectrum disorder (ASD) children with normal bowel function
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- autism spectrum disorder (ASD) children with bowel dysfunction
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Children diagnosed with Autism Spectrum Disorder (ASD), including those experiencing gastrointestinal symptoms such as constipation or diarrhea
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- raw counts
- Statistical test
- DESeq2
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Signature 1
Source: Figure 4 & Fig S4
Description: Bacterial taxa significantly associated with autism spectrum disorder (ASD) children with normal bowel function and autism spectrum disorder (ASD) children with bowel dysfunction by meta-analysis
Abundance in Group 1: increased abundance in autism spectrum disorder (ASD) children with bowel dysfunction
Revision editor(s): Ese
Signature 2
Source: Figure 4 & Fig S4
Description: Bacterial taxa significantly associated with autism spectrum disorder (ASD) children with normal bowel function and autism spectrum disorder (ASD) children with bowel dysfunction by meta-analysis
Abundance in Group 1: decreased abundance in autism spectrum disorder (ASD) children with bowel dysfunction
| NCBI | Quality Control | Links |
|---|---|---|
| t_157679t_157679 | ||
| Faecalibacterium prausnitzzi CFaecalibacterium prausnitzzi C |
Revision editor(s): Ese
