Characteristics of Oral-Gut Microbiota in Model Rats with CUMS-Induced Depression/Experiment 4
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2025-4-7
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Rattus norvegicus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces , Oral cavity Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces,Bucca,Buccal cavity,Cavity of mouth,Oral cavity,oral cavity
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Major depressive disorder major depression,major depressive disorder,recurrent major depression,single major depressive episode,unipolar depression,Major depressive disorder
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Higher sucrose preference
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Lower sucrose preference
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Rats subjected to chronic unpredictable mild stress (CUMS) exhibiting reduced sucrose preference, indicative of anhedonia and depression-like behavior
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Spearman Correlation
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2025-4-7
Source: Figure 6
Description: Differentially abundant bacteria between oral and gut flora with respect to their sucrose preference indicator
Abundance in Group 1: decreased abundance in Lower sucrose preference
| NCBI | Quality Control | Links |
|---|---|---|
| Vibrio |
Revision editor(s): Montana-D
