Characteristics of Oral-Gut Microbiota in Model Rats with CUMS-Induced Depression/Experiment 5

From BugSigDB


Reviewed Marked as Reviewed by Svetlana up on 2025-4-7

Curated date: 2025/04/04

Curator: Francisca

Revision editor(s): Francisca, Montana-D

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Rattus norvegicus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces , Oral cavity Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces,Bucca,Buccal cavity,Cavity of mouth,Oral cavity,oral cavity
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Major depressive disorder major depression,major depressive disorder,recurrent major depression,single major depressive episode,unipolar depression,Major depressive disorder
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Higher total distance traveled
Group 1 name Corresponds to the case (exposed) group for case-control studies
Lower total distance traveled
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Rats exposed to chronic unpredictable mild stress (CUMS) exhibiting reduced locomotor activity, indicative of depression-like behavior.

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V3-V4

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Spearman Correlation
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05


Signature 1

Reviewed Marked as Reviewed by Svetlana up on 2025-4-7

Curated date: 2025/04/04

Curator: Montana-D

Revision editor(s): Montana-D

Source: Figure 6

Description: Differentially abundant bacteria between oral and gut flora with respect to their Total distance indicator

Abundance in Group 1: increased abundance in Lower total distance traveled

NCBI Quality ControlLinks
Aerococcus
Psychrobacter

Revision editor(s): Montana-D

Signature 2

Reviewed Marked as Reviewed by Svetlana up on 2025-4-7

Curated date: 2025/04/05

Curator: Francisca

Revision editor(s): Francisca

Source: Figure 6

Description: Differentially abundant bacteria between oral and gut flora with respect to their Total distance indicator

Abundance in Group 1: decreased abundance in Lower total distance traveled

NCBI Quality ControlLinks
Rothia
Facklamia
Vibrio
Enterococcus
Streptococcus

Revision editor(s): Francisca