Gut microbiota differences in stunted and normal-lenght children aged 36-45 months in East Nusa Tenggara, Indonesia/Experiment 1

From BugSigDB


Needs review

Curated date: 2025/02/22

Curator: An05hka

Revision editor(s): An05hka

Subjects

Location of subjects
Indonesia
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Short stature Decreased body height,Height less than 3rd percentile,Short stature,Small stature,Stature below 3rd percentile,short stature
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Normal Length children
Group 1 name Corresponds to the case (exposed) group for case-control studies
Stunted Length children
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Stunted length children aged 36–45 months
Group 0 sample size Number of subjects in the control (unexposed) group
100
Group 1 sample size Number of subjects in the case (exposed) group
100

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V3-V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Kruskall-Wallis
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes

Alpha Diversity

Faith Phylogenetic diversity, takes into account phylogenetic distance of all taxa identified in a sample
decreased

Signature 1

Needs review

Curated date: 2025/02/23

Curator: An05hka

Revision editor(s): An05hka

Source: Figure 4.

Description: Boxplots of the 3 taxa at genus level that were significantly different between non-stunted and stunted children.

Abundance in Group 1: increased abundance in Stunted Length children

NCBI Quality ControlLinks
Faecalibacterium
Lachnoclostridium
Veillonella

Revision editor(s): An05hka