Effects of inulin on intestinal flora and metabolism-related indicators in obese polycystic ovary syndrome patients/Experiment 1
From BugSigDB
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Obesity Adiposis,Adiposity,Obese,Obese (finding),obesity,Obesity (disorder),Obesity [Ambiguous],obesity disease,obesity disorder,Obesity NOS,Obesity, unspecified,Overweight and obesity,Obesity
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Non-obese control group (NSD)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Obese control group (NFD)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- This group consists of obese patients with ≥ 25 kg/m2 body mass index (BMI).
- Group 0 sample size Number of subjects in the control (unexposed) group
- 20
- Group 1 sample size Number of subjects in the case (exposed) group
- 16
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 months
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Ion Torrent
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- LEfSe
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- 2
Signature 1
Source: Figure 3E
Description: Analysis of Biomarkers with significant differences between groups based on LDA Effect Size.
Abundance in Group 1: increased abundance in Obese control group (NFD)
| NCBI | Quality Control | Links |
|---|---|---|
| Allisonella | ||
| Parabacteroides distasonis | ||
| Howardella | ||
| [Ruminococcus] torques | ||
| Actinomyces massiliensis | ||
| TM7 phylum sp. oral clone FR058 | ||
| Megamonas |
Revision editor(s): Victoria
Signature 2
Source: Figure 3E
Description: Analysis of Biomarkers with significant differences between groups based on LDA Effect Size.
Abundance in Group 1: decreased abundance in Obese control group (NFD)
| NCBI | Quality Control | Links |
|---|---|---|
| Phocaeicola plebeius | ||
| unclassified Oscillospiraceae | ||
| Coprococcus eutactus |
Revision editor(s): Victoria
