Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals/Experiment 2

From BugSigDB


Needs review

Curated date: 2025/03/11

Curator: Tosin

Revision editor(s): Tosin

Subjects

Location of subjects
Italy
United Kingdom
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Diet Dietary,Diets,Diet,diet
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Omnivores
Group 1 name Corresponds to the case (exposed) group for case-control studies
Vegan
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Participants whose diet patterns excludes both meat, dairy and other animal products
Group 0 sample size Number of subjects in the control (unexposed) group
19817
Group 1 sample size Number of subjects in the case (exposed) group
656

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Wald Test
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.1
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Needs review

Curated date: 2025/03/12

Curator: Tosin

Revision editor(s): Tosin

Source: Figure 3h

Description: Meta-analysed correlations between SGB relative abundance and diet pattern between omnivores (n = 19,817 in pink) and vegans (n = 656 in green)

Abundance in Group 1: increased abundance in Vegan

NCBI Quality ControlLinks
Bacilli bacterium
Bacillota
Clostridium sp. AF20-17LB
Clostridium sp. AM33-3
Lachnospira
Lachnospiraceae bacterium
Oscillospiraceae
Roseburia hominis
Butyricicoccus sp. AM29-23AC
Clostridiaceae

Revision editor(s): Tosin

Signature 2

Needs review

Curated date: 2025/03/12

Curator: Tosin

Revision editor(s): Tosin

Source: Figure 3h

Description: Meta-analysed correlations between SGB relative abundance and diet pattern between omnivores (n = 19,817 in pink) and vegans (n = 656 in green)

Abundance in Group 1: decreased abundance in Vegan

NCBI Quality ControlLinks
Alistipes putredinis
Anaeromassilibacillus sp. An250
Candidatus Pararuminococcus gallinarum
Clostridia
Clostridia bacterium
Coprococcus comes
Erysipelotrichaceae bacterium
Merdimmobilis hominis
Odoribacter splanchnicus
Oscillospiraceae bacterium
Ruthenibacterium lactatiformans
unclassified Clostridia
Candidatus Avimicrobium caecorum
Bilophila wadsworthia
[Ruminococcus] torques
Lawsonibacter asaccharolyticus
Streptococcus thermophilus
Clostridiaceae bacterium

Revision editor(s): Tosin