Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals/Experiment 3

From BugSigDB


Needs review

Curated date: 2025/03/11

Curator: Victoria

Revision editor(s): Victoria

Subjects

Location of subjects
Italy
United Kingdom
United States of America
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Diet Dietary,Diets,Diet,diet
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Vegetarian
Group 1 name Corresponds to the case (exposed) group for case-control studies
Vegan
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Participants whose diet patterns exclude both meat, dairy and other animal products.
Group 0 sample size Number of subjects in the control (unexposed) group
1088
Group 1 sample size Number of subjects in the case (exposed) group
656

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Wald Test
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.1
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Needs review

Curated date: 2025/03/14

Curator: Victoria

Revision editor(s): Victoria

Source: Figure 4b

Description: Meta-analysed correlations between SGB relative abundance and diet pattern (vegetarian, n= 1,088 in purple vs vegan, n= 656 in green).

Abundance in Group 1: increased abundance in Vegan

NCBI Quality ControlLinks
Lachnospiraceae bacterium
Clostridia
Ruminococcus sp. AF41-9
Blautia sp. MSK.21.1
Bacillota

Revision editor(s): Victoria

Signature 2

Needs review

Curated date: 2025/03/14

Curator: Victoria

Revision editor(s): Victoria

Source: Figure 4b

Description: Meta-analysed correlations between SGB relative abundance and diet pattern (vegetarian, n= 1,088 in purple vs vegan, n= 656 in green).

Abundance in Group 1: decreased abundance in Vegan

NCBI Quality ControlLinks
Massiliimalia massiliensis
Parabacteroides goldsteinii
Bilophila wadsworthia
Erysipelotrichaceae bacterium
Holdemania sp. Marseille-P2844
Candidatus Borkfalkia ceftriaxoniphila
Lachnospiraceae bacterium
Clostridiaceae bacterium
Clostridia
Lactobacillus acidophilus
Lactococcus lactis
Evtepia gabavorous
Lacticaseibacillus paracasei
Lactobacillus delbrueckii
Bacillota
Lawsonibacter asaccharolyticus
[Ruminococcus] torques
Ruthenibacterium lactatiformans
Clostridia bacterium
Lacticaseibacillus rhamnosus
Oscillospiraceae bacterium
Streptococcus thermophilus

Revision editor(s): Victoria