Dietary selective effects manifest in the human gut microbiota from species composition to strain genetic makeup/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by KateRasheed on 2025-6-23
Subjects
- Location of subjects
- Germany
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Diet measurement Diet measurement,diet measurement
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Vegan
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Omnivore
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Omnivore refers to individuals regularly consuming a mixed diet of meat and meat products of ≥170 g/day).
- Group 0 sample size Number of subjects in the control (unexposed) group
- 33
- Group 1 sample size Number of subjects in the case (exposed) group
- 28
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- arcsine square-root
- Statistical test
- MaAsLin2
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.25
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
- Matched on Factors on which subjects have been matched on in a case-control study
- age, sex
Signature 1
Reviewed Marked as Reviewed by KateRasheed on 2025-6-23
Source: Supplementary Table 3A
Description: A panel of species that were differentially abundant in one diet type compared to the other.
Abundance in Group 1: decreased abundance in Omnivore
Revision editor(s): KateRasheed
Signature 2
Reviewed Marked as Reviewed by KateRasheed on 2025-6-23
Source: Supplementary Table 3A
Description: A panel of species that were differentially abundant in one diet type compared to the other.
Abundance in Group 1: increased abundance in Omnivore
Revision editor(s): KateRasheed
