Effects of vaginal microbiota on in vitro fertilization outcomes in women with different infertility causes/Experiment 10
From BugSigDB
Reviewed Marked as Reviewed by Svetlana up on 2025-4-8
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Vaginal fluid Vaginal discharge,Vaginal secretion,Vaginal fluid,vaginal fluid
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Body weight weight,Body weight,body weight
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- 18.5≤BMI<24 (Normal weight) group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- 24≤BMI<28 (Overweight) group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- This group consists of women with Polysystic ovary syndrome (PCOS) and are overweight.
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Signature 1
Reviewed Marked as Reviewed by Svetlana up on 2025-4-8
Source: Figure 4E
Description: Boxplot of the distribution of three bacterial genera based on their BMI levels.
Abundance in Group 1: increased abundance in 24≤BMI<28 (Overweight) group
NCBI | Quality Control | Links |
---|---|---|
Streptococcus |
Revision editor(s): Victoria