Different Efficacy of Five Soluble Dietary Fibers on Alleviating Loperamide-Induced Constipation in Mice: Influences of Different Structural Features/Experiment 5
From BugSigDB
Reviewed Marked as Reviewed by KateRasheed on 2025-5-5
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Mus musculus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Caecum Blind intestine,Blindgut,Caeca,Caecum,Ceca,Cecum,Intestinum caecum,Intestinum crassum caecum,Intestinum crassum cecum,caecum
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Response to diet Response to diet,response to diet
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Model control group (MC)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Polydextrose group (PD)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Male ICR mice administered to Polydextrose group (PD), the corresponding soluble fibers at doses of 400 mg/kg bw/d
- Group 0 sample size Number of subjects in the control (unexposed) group
- 12
- Group 1 sample size Number of subjects in the case (exposed) group
- 12
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Kruskall-Wallis
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Chao1 Abundance-based estimator of species richness
- unchanged
Signature 1
Reviewed Marked as Reviewed by KateRasheed on 2025-5-5
Source: Figures 4B,C,D,E,F,G,J-L
Description: Relative Abundance of genera in the gut microbiota of mice
Abundance in Group 1: increased abundance in Polydextrose group (PD)
| NCBI | Quality Control | Links |
|---|---|---|
| Alistipes | ||
| Mucispirillum | ||
| Oscillibacter | ||
| Ruminococcus | ||
| unclassified Bacillota | ||
| unclassified Desulfovibrionaceae | ||
| unclassified Oscillospiraceae |
Revision editor(s): Miss Lulu
