Newly identified species from the dog dental plaque microbiome highlight little overlap with humans/Experiment 1
From BugSigDB
Subjects
- Location of subjects
- Serbia
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Canis lupus familiaris
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Oral cavity Bucca,Buccal cavity,Cavity of mouth,Oral cavity,oral cavity
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Species design species_design,Species design,species design
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Supragingival dental plaque from humans
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Supragingival dental plaque from dogs
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Clinically healthy dogs with no signs of oral disease (e.g., gingivitis, periodontitis) after oral health assessment was performed at the Faculty of Veterinary Medicine, University of Belgrade
- Group 0 sample size Number of subjects in the control (unexposed) group
- 154
- Group 1 sample size Number of subjects in the case (exposed) group
- 64
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 4 weeks
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Signature 1
Source: Text, Paragraph 8
Description: Differentially abundant species found in Supragingival dental plaque of dogs and humans
Abundance in Group 1: increased abundance in Supragingival dental plaque from dogs
NCBI | Quality Control | Links |
---|---|---|
Campylobacter rectus |
Revision editor(s): Ese
Signature 2
Source: Text, Paragraph 8
Description: Differentially abundant species found in Supragingival dental plaque of dogs and humans
Abundance in Group 1: decreased abundance in Supragingival dental plaque from dogs
NCBI | Quality Control | Links |
---|---|---|
Fusobacterium periodonticum |
Revision editor(s): Ese