Roseburia hominis improves host metabolism in diet-induced obesity/Experiment 11

From BugSigDB


Needs review

Curated date: 2025/04/11

Curator: Z.uk.a

Revision editor(s): Z.uk.a, Victoria

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Mus musculus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Triglyceride C6H5O6R3,Triacylglycerol,triacylglycerols,Triglycerid,Triglyceride,triglycerides,Triglyzerid,triglyceride
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Low Hepatic triglycerides
Group 1 name Corresponds to the case (exposed) group for case-control studies
High Hepatic triglycerides
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
The mice in group 1 consists of mice with High levels of hepatic triglycerides
Group 0 sample size Number of subjects in the control (unexposed) group
5
Group 1 sample size Number of subjects in the case (exposed) group
5

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Spearman Correlation
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Needs review

Curated date: 2025/04/14

Curator: Z.uk.a

Revision editor(s): Z.uk.a

Source: Figure 4E

Description: Hepatic triglyceride correlation of differential species in mice between the HFD-PBS and HFD-RH groups

Abundance in Group 1: increased abundance in High Hepatic triglycerides

NCBI Quality ControlLinks
Faecalibaculum rodentium
Romboutsia ilealis
Staphylococcus xylosus
Eggerthella sp. HF 1101Eggerthella sp. HF 1101
Berryella intestinalis

Revision editor(s): Z.uk.a

Signature 2

Needs review

Curated date: 2025/04/14

Curator: Z.uk.a

Revision editor(s): Z.uk.a

Source: Figure 4E

Description: Hepatic triglyceride levels exhibit differential correlations with species in mice between the HFD-PBS and HFD-RH groups

Abundance in Group 1: decreased abundance in High Hepatic triglycerides

NCBI Quality ControlLinks
Dysosmobacter welbionis
Faecalibacterium prausnitzii
Lactobacillus johnsonii
Oscillibacter sp. PEA192
Oscillibacter valericigenes
Parabacteroides goldsteinii
Turicimonas muris

Revision editor(s): Z.uk.a