Roseburia hominis improves host metabolism in diet-induced obesity/Experiment 12
From BugSigDB
Reviewed Marked as Reviewed by KateRasheed on 2025-8-11
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Mus musculus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Response to high fat food intake Response to high fat food intake,response to high fat food intake
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- High Fat Diet- Roseburia hominis (HFD-RH) mice at baseline
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Fat Diet- Roseburia hominis (HFD-RH) mice at endpoint
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Mice were characterized after the intervention of Roseburia hominis for 11 weeks
- Group 0 sample size Number of subjects in the control (unexposed) group
- 5
- Group 1 sample size Number of subjects in the case (exposed) group
- 5
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Signature 1
Reviewed Marked as Reviewed by KateRasheed on 2025-8-11
Source: Figure S2B
Description: The change of relative abundance of Roseburia hominis in HFD-fed mice before and after the intervention for 11 weeks.
Abundance in Group 1: increased abundance in High Fat Diet- Roseburia hominis (HFD-RH) mice at endpoint
| NCBI | Quality Control | Links |
|---|---|---|
| Roseburia hominis |
Revision editor(s): Ese
