Roseburia hominis improves host metabolism in diet-induced obesity/Experiment 9

From BugSigDB


Needs review

Curated date: 2025/04/11

Curator: Z.uk.a

Revision editor(s): Z.uk.a

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Mus musculus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Alanine measurement Alanine measurement,alanine measurement
Group 0 name Corresponds to the control (unexposed) group for case-control studies
High in alanine transaminase
Group 1 name Corresponds to the case (exposed) group for case-control studies
Low in alanine transaminase
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Mice in this group are characterized by low levels of alanine transaminase enzymes
Group 0 sample size Number of subjects in the control (unexposed) group
5
Group 1 sample size Number of subjects in the case (exposed) group
5

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Spearman Correlation
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Needs review

Curated date: 2025/04/14

Curator: Z.uk.a

Revision editor(s): Z.uk.a

Source: Figure 4E

Description: Alanine transaminase correlation of differential species in mice between the HFD-PBS and HFD-RH groups

Abundance in Group 1: increased abundance in Low in alanine transaminase

NCBI Quality ControlLinks
Faecalibaculum rodentium

Revision editor(s): Z.uk.a

Signature 2

Needs review

Curated date: 2025/04/14

Curator: Z.uk.a

Revision editor(s): Z.uk.a

Source: Figure 4E

Description: Alanine transaminase correlation of differential species in mice between the HFD-PBS and HFD-RH groups

Abundance in Group 1: decreased abundance in Low in alanine transaminase

NCBI Quality ControlLinks
Herbinix luporum
Lachnoclostridium sp. YL32
Butyrivibrio fibrisolvens
[Clostridium] innocuum
Lactobacillus johnsonii

Revision editor(s): Z.uk.a