Correlations Between Amelioration of Rotenone-Induced Parkinson's Symptoms by Amomum tsaoko Flavonoids and Gut Microbiota in Mice/Experiment 8

From BugSigDB


Needs review

Curated date: 2025/04/14

Curator: Tosin

Revision editor(s): Tosin

Subjects

Location of subjects
China
Host species Species from which microbiome was sampled. Contact us to have more species added.
Mus musculus
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Regulation of defecation Regulation of defecation,regulation of defecation
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Fecal black stool time (FBST) Decreased
Group 1 name Corresponds to the case (exposed) group for case-control studies
Fecal black stool time (FBST) Increased
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
High levels of fecal black stool time

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V3-V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Spearman Correlation
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Needs review

Curated date: 2025/04/14

Curator: Tosin

Revision editor(s): Tosin

Source: Figure 8B

Description: Correlations between differential genera and defecation parameters. The color at each point of intersection indicates the value of the r coefficient (n = 8).

Abundance in Group 1: increased abundance in Fecal black stool time (FBST) Increased

NCBI Quality ControlLinks
Blautia
Desulfovibrio
Erysipelotrichaceae
Intestinimonas
Lachnospiraceae bacterium NK4A136
Prevotellaceae UCG-001Prevotellaceae UCG-001

Revision editor(s): Tosin

Signature 2

Needs review

Curated date: 2025/04/14

Curator: Tosin

Revision editor(s): Tosin

Source: Figure 8B

Description: Correlations between differential genera and defecation parameters. The color at each point of intersection indicates the value of the r coefficient (n = 8).

Abundance in Group 1: decreased abundance in Fecal black stool time (FBST) Increased

NCBI Quality ControlLinks
Bifidobacterium
Faecalibaculum
Paludicola
Parvibacter

Revision editor(s): Tosin