Why do babies cry? Exploring the role of the gut microbiota in infantile colic, constipation, and cramps in the KOALA birth cohort study
-
Quality control
- Retracted paper
- Contamination issues suspected
- Batch effect issues suspected
- Uncontrolled confounding suspected
- Results are suspect (various reasons)
- Tags applied
Experiment 1
Subjects
- Location of subjects
- Netherlands
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Functional abnormality of the gastrointestinal tract Functional abnormality of the GI tract,GI dysfunction,Functional abnormality of the gastrointestinal tract,functional abnormality of the gastrointestinal tract
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-crude (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation > 3d-crude (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation: >3 days without defecation in infants <3 months. (full cohort).
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 months.
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- centered log-ratio
- Statistical test
- Logistic Regression
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High constipation > 3d-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Enterococcus |
Revision editor(s): Shulamite
Signature 2
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High constipation > 3d-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Haemophilus | ||
Lactococcus | ||
Staphylococcus |
Revision editor(s): Shulamite
Experiment 2
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-crude (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-crude (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic: Wessel's criteria applied to infants <3 months. (Full cohort)
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): Shulamite
Signature 2
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High colic: wessel-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Bifidobacterium | ||
Sutterella |
Revision editor(s): Shulamite
Experiment 3
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-crude (4 - 7months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-crude (4 - 7months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic: Wessel's criteria applied to infants aged 4–7 months. (Full cohort).
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-crude (4 - 7months)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): Shulamite
Experiment 4
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-crude (8 - 12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation >3d-crude (8 - 12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation: >3 days without defecation in infants aged 8–12 months (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High constipation >3d-crude (8 - 12months)
NCBI | Quality Control | Links |
---|---|---|
Parabacteroides |
Revision editor(s): Shulamite
Experiment 5
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-Covariate adjusted (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-Covariate adjusted (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic: Wessel's criteria applied to infants <3 months, adjusted for covariates. (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High colic: wessel-Covariate adjusted (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Bifidobacterium |
Revision editor(s): Shulamite
Experiment 6
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-Covariate adjusted (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation > 3d-Covariate adjusted (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation: >3 days without defecation in infants <3 months, adjusted for covariates (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High constipation > 3d-Covariate adjusted (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Haemophilus | ||
Staphylococcus |
Revision editor(s): Shulamite
Experiment 7
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low cramps >3d-Covariate adjusted (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High cramps >3d-Covariate adjusted (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High cramps: Occurrence >3 days in infants <3 months, adjusted for covariates (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High cramps >3d-Covariate adjusted (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Enterobacteriaceae |
Revision editor(s): Shulamite
Experiment 8
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-Covariate adjusted (4 - 7months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-Covariate adjusted (4 - 7months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic: Wessel's criteria applied to infants aged 4–7 months, adjusted for covariates (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-Covariate adjusted (4 - 7months)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): Shulamite
Experiment 9
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low cramps >3d-Covariate adjusted
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High cramps >3d-Covariate adjusted (4 - 7months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High cramps: Occurrence >3 days in infants aged 4–7 months, adjusted for covariates (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High cramps >3d-Covariate adjusted (4 - 7months)
NCBI | Quality Control | Links |
---|---|---|
Clostridium SS1Clostridium SS1 |
Revision editor(s): Shulamite
Experiment 10
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-Covariate adjusted (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-Covariate adjusted (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic: Wessel's criteria were applied to infants aged 8–12 months, and they were adjusted for covariates (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High colic: wessel-Covariate adjusted (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Enterococcus |
Revision editor(s): Shulamite
Experiment 11
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-Covariate adjusted (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation > 3d-Covariate adjusted (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation: >3 days without defecation in infants aged 8–12 months, adjusted for covariates (Full cohort).
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High constipation > 3d-Covariate adjusted (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Parabacteroides |
Revision editor(s): Shulamite
Experiment 12
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low cramps >3d-Covariate adjusted (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High cramps >3d-Covariate adjusted (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High cramps: Occurrence >3 days in infants aged 8–12 months, adjusted for covariates (Full cohort).
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High cramps >3d-Covariate adjusted (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Enterococcus | ||
Clostridium SS1Clostridium SS1 |
Revision editor(s): Shulamite
Experiment 13
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-crude (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-crude (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic (Wessel’s criteria, crude model) in infants <3 months, with no abx up to 3 months.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Sutterella | ||
Mediterraneibacter gnavus |
Revision editor(s): Shulamite
Signature 2
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High colic: wessel-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Bifidobacterium |
Revision editor(s): Shulamite
Experiment 14
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-crude (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation > 3d-crude (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation (>3 days without defecation, crude model) in infants <3 months, with no abx up to 3 months.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High constipation > 3d-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Enterococcus |
Revision editor(s): Shulamite
Signature 2
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High constipation > 3d-crude (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Lactococcus | ||
Staphylococcus |
Revision editor(s): Shulamite
Experiment 15
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-crude (4 - 7months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-crude (4 - 7months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic (Wessel’s criteria, crude model) in infants aged 4–7 months, with no abx up to 3 months.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-crude (4 - 7months)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): Shulamite
Experiment 16
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-crude (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-crude (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic (Wessel’s criteria, crude model) in infants aged 8–12 months, with no abx up to 3 months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-crude (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Veillonella |
Revision editor(s): Shulamite
Experiment 17
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-crude (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation > 3d-crude (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation (>3 days without defecation, crude model) in infants aged 8–12 months, with no abx up to 3 months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High constipation > 3d-crude (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Parabacteroides |
Revision editor(s): Shulamite
Experiment 18
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-Covariate adjusted (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-Covariate adjusted (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic (Wessel’s criteria, covariate-adjusted model) in infants <3 months, with no abx up to 3 months.
Lab analysis
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Not specified
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-Covariate adjusted (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Enterobacteriaceae |
Revision editor(s): Shulamite
Experiment 19
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-Covariate adjusted (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation > 3d-Covariate adjusted (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation (>3 days without defecation, covariate-adjusted model) in infants <3 months, with no abx up to 3 months.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 months.
Lab analysis
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High constipation > 3d-Covariate adjusted (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus |
Revision editor(s): Shulamite
Experiment 20
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Colic:Wessel crude <3 months (Full cohort)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Colic:Wessel adjusted <3 months (Full cohort)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Colic:Wessel covariate Adjusted <3months in the Full cohort
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 months
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel crude <3 months (Full cohort) and Colic:Wessel adjusted <3 months (Full cohort)
Abundance in Group 1: increased abundance in Colic:Wessel adjusted <3 months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel crude <3 months (Full cohort) and Colic:Wessel adjusted <3 months (Full cohort)
Abundance in Group 1: decreased abundance in Colic:Wessel adjusted <3 months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus | ||
Lactobacillus | ||
Bifidobacterium |
Revision editor(s): MyleeeA
Experiment 21
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Treatment Treatment,treatment
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Colic:Wessel No Antibiotics crude <3 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Colic:Wessel No Antibiotics adjusted <3 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Colic:Wessel covariate Adjusted No Antibiotics <3months group
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel No Antibiotics crude <3 months and Colic:Wessel No Antibiotics adjusted <3 months.
Abundance in Group 1: increased abundance in Colic:Wessel No Antibiotics adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel No Antibiotics crude <3 months and Colic:Wessel No Antibiotics adjusted <3 months.
Abundance in Group 1: decreased abundance in Colic:Wessel No Antibiotics adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus | ||
Bifidobacterium | ||
Lactobacillus |
Revision editor(s): MyleeeA
Experiment 22
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Breastfeeding duration Breastfeeding duration,breastfeeding duration
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Colic:Wessel Breastfed crude <3 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Colic:Wessel Breastfed adjusted <3 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Colic:Wessel Covariate adjusted <3 months Breastfed group.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel Breastfed <3 months and Colic:Wessel Breastfed adjusted <3 months.
Abundance in Group 1: increased abundance in Colic:Wessel Breastfed adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel Breastfed <3 months and Colic:Wessel Breastfed adjusted <3 months.
Abundance in Group 1: decreased abundance in Colic:Wessel Breastfed adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Lactobacillus |
Revision editor(s): MyleeeA
Experiment 23
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Functional abnormality of the gastrointestinal tract Functional abnormality of the GI tract,GI dysfunction,Functional abnormality of the gastrointestinal tract,functional abnormality of the gastrointestinal tract
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Colic:Wessel crude 4-7 months (Full cohort)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Colic:Wessel adjusted 4-7months (Full cohort)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Colic:Wessel covariate Adjusted 4-7 months in the Full cohort
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations betweenColic:Wessel crude 4-7 months (Full cohort) and Colic:Wessel adjusted 4-7 months (Full cohort).
Abundance in Group 1: increased abundance in Colic:Wessel adjusted 4-7months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus | ||
Staphylococcus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations betweenColic:Wessel crude 4-7 months (Full cohort) and Colic:Wessel adjusted 4-7 months (Full cohort).
Abundance in Group 1: decreased abundance in Colic:Wessel adjusted 4-7months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Bifidobacterium | ||
Lactobacillus |
Revision editor(s): MyleeeA
Experiment 24
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Treatment Treatment,treatment
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Colic:Wessel No Antibiotics crude 4-7 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Colic:Wessel No Antibiotics adjusted 4-7 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Colic:Wessel covariate Adjusted No Antibiotics 4-7 months group
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel No Antibiotics crude 4-7 months and Colic:Wessel No Antibiotics adjusted 4-7 months.
Abundance in Group 1: increased abundance in Colic:Wessel No Antibiotics adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel No Antibiotics crude 4-7 months and Colic:Wessel No Antibiotics adjusted 4-7 months.
Abundance in Group 1: decreased abundance in Colic:Wessel No Antibiotics adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Lactobacillus | ||
Bifidobacterium |
Revision editor(s): MyleeeA
Experiment 25
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Breastfeeding duration Breastfeeding duration,breastfeeding duration
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Colic:Wessel Breastfed crude 4-7 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Colic:Wessel Breastfed adjusted 4-7 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Colic:Wessel Covariate adjusted 4-7 months Breastfed group.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel Breastfed crude 4-7 months and Colic:Wessel Breastfed adjusted 4-7 months.
Abundance in Group 1: increased abundance in Colic:Wessel Breastfed adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Colic:Wessel Breastfed crude 4-7 months and Colic:Wessel Breastfed adjusted 4-7 months.
Abundance in Group 1: decreased abundance in Colic:Wessel Breastfed adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Lactobacillus |
Revision editor(s): MyleeeA
Experiment 26
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Constipation Constipation,Costiveness,Dyschezia,constipation
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Constipation >3d crude <3 months (Full cohort)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Constipation >3d adjusted <3 months (Full cohort)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Constipation >3d covariate Adjusted <3months in the Full cohort
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d crude <3 months (Full cohort) and Constipation >3d adjusted <3 months (Full cohort)
Abundance in Group 1: increased abundance in Constipation >3d adjusted <3 months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d crude <3 months (Full cohort) and Constipation >3d adjusted <3 months (Full cohort)
Abundance in Group 1: decreased abundance in Constipation >3d adjusted <3 months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Bifidobacterium | ||
Staphylococcus | ||
Lactobacillus |
Revision editor(s): MyleeeA
Experiment 27
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Treatment Treatment,treatment
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Constipation >3d No Antibiotics crude <3 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Constipation >3d No Antibiotics adjusted <3 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Constipation >3d covariate Adjusted <3months in the No Antibiotics group.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d No Antibiotics crude <3 months and Constipation >3d No Antibiotics adjusted <3 months
Abundance in Group 1: increased abundance in Constipation >3d No Antibiotics adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d No Antibiotics crude <3 months and Constipation >3d No Antibiotics adjusted <3 months
Abundance in Group 1: decreased abundance in Constipation >3d No Antibiotics adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus | ||
Lactobacillus | ||
Bifidobacterium |
Revision editor(s): MyleeeA
Experiment 28
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Breastfeeding duration Breastfeeding duration,breastfeeding duration
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Constipation >3d Breastfed crude <3 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Constipation >3d Breastfed adjusted <3 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Constipation >3d Covariate adjusted <3 months Breastfed group.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d Breastfed crude <3 months and Constipation >3d Breastfed adjusted <3 months
Abundance in Group 1: increased abundance in Constipation >3d Breastfed adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Lactobacillus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d Breastfed crude <3 months and Constipation >3d Breastfed adjusted <3 months
Abundance in Group 1: decreased abundance in Constipation >3d Breastfed adjusted <3 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus | ||
Staphylococcus | ||
Bifidobacterium |
Revision editor(s): MyleeeA
Experiment 29
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Constipation Constipation,Costiveness,Dyschezia,constipation
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Constipation >3d crude 4-7 months (Full cohort)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Constipation >3d adjusted 4-7 months (Full cohort)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Constipation >3d covariate Adjusted 4-7 months in the Full cohort
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d crude 4-7 months (Full cohort) and Constipation >3d adjusted 4-7 months (Full cohort).
Abundance in Group 1: increased abundance in Constipation >3d adjusted 4-7 months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d crude 4-7 months (Full cohort) and Constipation >3d adjusted 4-7 months (Full cohort).
Abundance in Group 1: decreased abundance in Constipation >3d adjusted 4-7 months (Full cohort)
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus | ||
Lactobacillus | ||
Bifidobacterium |
Revision editor(s): MyleeeA
Experiment 30
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Breastfeeding duration Breastfeeding duration,breastfeeding duration
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Constipation >3d Breastfed crude 4-7 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Constipation >3d Breastfed adjusted 4-7 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Constipation >3d Covariate adjusted 4-7 months Breastfed group.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d Breastfed crude 4-7 months and Constipation >3d Breastfed adjusted 4-7 months.
Abundance in Group 1: increased abundance in Constipation >3d Breastfed adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d Breastfed crude 4-7 months and Constipation >3d Breastfed adjusted 4-7 months
Abundance in Group 1: decreased abundance in Constipation >3d Breastfed adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus | ||
Lactobacillus | ||
Bifidobacterium |
Revision editor(s): MyleeeA
Experiment 31
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Treatment Treatment,treatment
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Constipation >3d No Antibiotics crude 4-7 months
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Constipation >3d No Antibiotics adjusted 4-7 months
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Constipation >3d covariate Adjusted No Antibiotics 4-7 months group
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d No antibiotics crude 4-7 months and Constipation >3d No antibiotics adjusted 4-7 months
Abundance in Group 1: increased abundance in Constipation >3d No Antibiotics adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Signature 2
Source: Figure 5C
Description: Results of regression model testing associations between Constipation >3d No antibiotics crude 4-7 months and Constipation >3d No antibiotics adjusted 4-7 months
Abundance in Group 1: decreased abundance in Constipation >3d No Antibiotics adjusted 4-7 months
NCBI | Quality Control | Links |
---|---|---|
Lactobacillus | ||
Staphylococcus |
Revision editor(s): MyleeeA
Experiment 32
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Breastfeeding duration Breastfeeding duration,breastfeeding duration
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Constipation <3d Breastfed >3months (Crude)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Constipation <3d Breastfed >3months (Crude)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, had constipation <3days, were >3months and were in the crude group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Constipation <3days, >3 months Breastfed (Crude) stool microbiota core genera
Abundance in Group 1: decreased abundance in High Constipation <3d Breastfed >3months (Crude)
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus |
Revision editor(s): MyleeeA
Experiment 33
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Cramps <3d Breastfed >3months (Crude)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Cramps <3d Breastfed >3months (Crude)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, had cramps <3days, were >3months and were in the crude group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Cramps <3days, >3 months Breastfed (Crude) stool microbiota core genera
Abundance in Group 1: decreased abundance in High Cramps <3d Breastfed >3months (Crude)
NCBI | Quality Control | Links |
---|---|---|
Enterobacteriaceae |
Revision editor(s): MyleeeA
Experiment 34
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Colic:Wessel Breastfed 4-7months (Crude)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Colic:Wessel Breastfed 4-7months (Crude)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, were Colic:Wessel 4-7 months and were in the crude group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Colic:Wessel Breastfed 4-7 months (Crude) stool microbiota core genera
Abundance in Group 1: increased abundance in High Colic:Wessel Breastfed 4-7months (Crude)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Experiment 35
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Colic:Wessel Breastfed 8-12months (Crude)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Colic:Wessel Breastfed 8-12months (Crude)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, were Colic:Wessel 8-12 months and were in the crude group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Colic:Wessel Breastfed 8-12 months (Crude) stool microbiota core genera
Abundance in Group 1: decreased abundance in High Colic:Wessel Breastfed 8-12months (Crude)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Experiment 36
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Colic:Wessel Breastfed >3months (Covariate adjusted)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Colic:Wessel Breastfed >3months (Covariate adjusted)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, were Colic:Wessel >3 months and were in the Covariate adjusted group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Colic:Wessel Breastfed >3 months (Covariate adjusted) stool microbiota core genera
Abundance in Group 1: decreased abundance in High Colic:Wessel Breastfed >3months (Covariate adjusted)
NCBI | Quality Control | Links |
---|---|---|
Sutterella |
Revision editor(s): MyleeeA
Experiment 37
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Constipation <3d Breastfed >3months (Covariate adjusted)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Low Constipation <3d Breastfed >3months (Covariate adjusted)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, had constipation <3days, were >3months and were in the Covariate adjusted group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Constipation <3days, >3 months Breastfed (Covariate adjusted) stool microbiota core genera
Abundance in Group 1: decreased abundance in Low Constipation <3d Breastfed >3months (Covariate adjusted)
NCBI | Quality Control | Links |
---|---|---|
Staphylococcus |
Revision editor(s): MyleeeA
Experiment 38
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Cramps <3d Breastfed >3months (Covariate adjusted)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Low Cramps <3d Breastfed >3months (Covariate adjusted)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, had cramps <3days, were >3months and were in the Covariate adjusted group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Cramps <3days, >3 months Breastfed (Covariate adjusted) stool microbiota core genera
Abundance in Group 1: decreased abundance in Low Cramps <3d Breastfed >3months (Covariate adjusted)
NCBI | Quality Control | Links |
---|---|---|
Enterobacteriaceae |
Revision editor(s): MyleeeA
Experiment 39
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Colic:Wessel Breastfed 4-7 months (Covariate adjusted)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High Colic:Wessel Breastfed 4-7 months (Covariate adjusted)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, were Colic:Wessel 4-7 months and were in the Covariate adjusted group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Colic:Wessel Breastfed 4-7 months (Covariate adjusted) stool microbiota core genera
Abundance in Group 1: increased abundance in High Colic:Wessel Breastfed 4-7 months (Covariate adjusted)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Experiment 40
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low Colic:Wessel Breastfed 8-12months (Covariate adjusted)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Low Colic:Wessel Breastfed 8-12months (Covariate adjusted)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Infants who were exclusively breastfed before sampling, were Colic:Wessel 8-12 months and were in the Covariate adjusted group.
Lab analysis
Statistical Analysis
Signature 1
Source: Supplementary Table 6: Part C
Description: Results of regression model testing associations between Colic:Wessel Breastfed 8-12 months (Covariate adjusted) stool microbiota core genera
Abundance in Group 1: decreased abundance in Low Colic:Wessel Breastfed 8-12months (Covariate adjusted)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): MyleeeA
Experiment 41
Subjects
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Functional abnormality of the gastrointestinal tract Functional abnormality of the GI tract,GI dysfunction,Functional abnormality of the gastrointestinal tract,functional abnormality of the gastrointestinal tract
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low cramps >3d-Covariate adjusted (< 3months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High cramps >3d-Covariate adjusted (< 3months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High cramps (>3 days of symptoms, covariate-adjusted model) in infants <3 months, with no abx up to 3 months.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High cramps >3d-Covariate adjusted (< 3months)
NCBI | Quality Control | Links |
---|---|---|
Enterobacteriaceae |
Revision editor(s): Shulamite
Experiment 42
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-Covariate adjusted (4 - 7months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-Covariate adjusted (4 - 7months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic (Wessel’s criteria, covariate-adjusted model) in infants aged 4–7 months, with no abx up to 3 months.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High colic: wessel-Covariate adjusted (4 - 7months)
NCBI | Quality Control | Links |
---|---|---|
Mediterraneibacter gnavus |
Revision editor(s): Shulamite
Experiment 43
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low cramps >3d-Covariate adjusted (4 - 7months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High cramps >3d-Covariate adjusted (4 - 7months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High cramps (>3 days of symptoms, covariate-adjusted model) in infants aged 4–7 months, with no abx up to 3 months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High cramps >3d-Covariate adjusted (4 - 7months)
NCBI | Quality Control | Links |
---|---|---|
Clostriidium SS1Clostriidium SS1 |
Revision editor(s): Shulamite
Experiment 44
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low colic: wessel-Covariate adjusted (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High colic: wessel-Covariate adjusted (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High colic (Wessel’s criteria, covariate-adjusted model) in infants aged 8–12 months, with no abx up to 3 months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High colic: wessel-Covariate adjusted (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Enterococcus |
Revision editor(s): Shulamite
Experiment 45
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low constipation >3d-Covariate adjusted (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High constipation > 3d-Covariate adjusted (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High constipation (>3 days without defecation, covariate-adjusted model) in infants aged 8–12 months, with no abx up to 3 months.
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: increased abundance in High constipation > 3d-Covariate adjusted (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Parabacteroides |
Revision editor(s): Shulamite
Experiment 46
Subjects
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Low cramps >3d-Covariate adjusted (8-12months)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- High cramps >3d-Covariate adjusted (8-12months)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- High cramps (>3 days of symptoms, covariate-adjusted model) in infants aged 8–12 months, with no abx up to 3 months.
Lab analysis
Statistical Analysis
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- unchanged
Signature 1
Source: Table S6
Description: Results of regression models testing associations between one-month stool microbiota core genera and functional gastrointestinal symptoms.
Abundance in Group 1: decreased abundance in High cramps >3d-Covariate adjusted (8-12months)
NCBI | Quality Control | Links |
---|---|---|
Enterococcus | ||
Clostridium SS1Clostridium SS1 |
Revision editor(s): Shulamite
Contents
- 1 Experiment 1
- 2 Experiment 2
- 3 Experiment 3
- 4 Experiment 4
- 5 Experiment 5
- 6 Experiment 6
- 7 Experiment 7
- 8 Experiment 8
- 9 Experiment 9
- 10 Experiment 10
- 11 Experiment 11
- 12 Experiment 12
- 13 Experiment 13
- 14 Experiment 14
- 15 Experiment 15
- 16 Experiment 16
- 17 Experiment 17
- 18 Experiment 18
- 19 Experiment 19
- 20 Experiment 20
- 21 Experiment 21
- 22 Experiment 22
- 23 Experiment 23
- 24 Experiment 24
- 25 Experiment 25
- 26 Experiment 26
- 27 Experiment 27
- 28 Experiment 28
- 29 Experiment 29
- 30 Experiment 30
- 31 Experiment 31
- 32 Experiment 32
- 33 Experiment 33
- 34 Experiment 34
- 35 Experiment 35
- 36 Experiment 36
- 37 Experiment 37
- 38 Experiment 38
- 39 Experiment 39
- 40 Experiment 40
- 41 Experiment 41
- 42 Experiment 42
- 43 Experiment 43
- 44 Experiment 44
- 45 Experiment 45
- 46 Experiment 46