Effects of OsomeFood Clean Label plant-based meals on the gut microbiome/Experiment 1
From BugSigDB
Subjects
- Location of subjects
- Singapore
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Health study participation health questionnaire participation,health survey participation,Health study participation,health study participation
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Participants before the AWE diet
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Participants after the AWE diet
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Participants who strictly adhered to OsomeFoods plant-based meal plans for five consecutive days (Monday through to Friday; 'AWE') for 3 weeks. AWE means sticking with the diet all through from Monday to Friday
- Group 0 sample size Number of subjects in the control (unexposed) group
- 10
- Group 1 sample size Number of subjects in the case (exposed) group
- 10
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 3 Months before the study
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
Signature 1
Source: Fig 2c
Description: Species differentially abundant between baseline and day 21 (End of the intervention period)
Abundance in Group 1: increased abundance in Participants after the AWE diet
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroides thetaiotaomicron | ||
| Bacteroides xylanisolvens | ||
| Leuconostoc garlicum |
Revision editor(s): ModinatG
Signature 2
Source: Fig 2c
Description: Species differentially abundant between baseline and day 21 (End of the intervention period)
Abundance in Group 1: decreased abundance in Participants after the AWE diet
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroides phage B124-14 | ||
| Collinsella intestinalis | ||
| Romboutsia ilealis | ||
| Weissella confusa |
Revision editor(s): ModinatG
