Changes in the vaginal microbiota across a gradient of urbanization/Experiment 12

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Curated date: 2024/11/20

Curator: Tosin

Revision editor(s): Tosin

Subjects

Location of subjects

Venezuela

Host species Species from which microbiome was sampled. Contact us to have more species added.

Homo sapiens

Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology

Vagina Vagina,vagina,Distal oviductal region,Distal portion of oviduct,Vaginae

Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology

Lifestyle measurement Lifestyle measurement,lifestyle measurement

Group 0 name Corresponds to the control (unexposed) group for case-control studies

Amerindians

Group 1 name Corresponds to the case (exposed) group for case-control studies

Mestizos

Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group

Mestizo women that have sexual practices other than vaginal, sexual contact with mestizo men, and use of vaginal douche.

Group 0 sample size Number of subjects in the control (unexposed) group

15

Group 1 sample size Number of subjects in the case (exposed) group

27

Lab analysis

Sequencing type

16S

16S variable region One or more hypervariable region(s) of the bacterial 16S gene

V1-V3

Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance

Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).

relative abundances

Statistical test

LEfSe

Significance threshold p-value or FDR threshold used for differential abundance testing (if any)

0.05

MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?

No