Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice/Experiment 2
From BugSigDB
Needs review
Subjects
- Location of subjects
- United States of America
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Mus musculus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Response to ketogenic diet Response to ketogenic diet,response to ketogenic diet
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- control diet group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- KD3:1 group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Mice fed a ketogenic diet of 3:1 fat to protein ratio
- Group 0 sample size Number of subjects in the control (unexposed) group
- 4
- Group 1 sample size Number of subjects in the case (exposed) group
- 4
Lab analysis
- Sequencing type
- PCR
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Statistical test
- Kruskall-Wallis
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
Alpha Diversity
- Pielou Quantifies how equal the community is numerically
- unchanged
- Shannon Estimator of species richness and species evenness: more weight on species richness
- unchanged
- Richness Number of species
- increased
Signature 1
Needs review
Source: Figure 2a
Description: Comparing difference in fecal microbiome of rats undergoing KD3:1 diet vs rats with a control diet
Abundance in Group 1: decreased abundance in KD3:1 group
| NCBI | Quality Control | Links |
|---|---|---|
| Actinomycetota |
Revision editor(s): Kavyaayala
Signature 2
Needs review
Source: Figure 2a
Description: Comparing difference in fecal microbiome of rats undergoing KD4:1 diet vs rats with a control diet
Abundance in Group 1: increased abundance in KD3:1 group
| NCBI | Quality Control | Links |
|---|---|---|
| Deferribacteres |
Revision editor(s): Kavyaayala
