Relationship between acetaldehyde concentration in mouth air and characteristics of microbiota of tongue dorsum in Japanese healthy adults: a cross-sectional study/Experiment 1

From BugSigDB


Needs review

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): WikiWorks

Subjects

Location of subjects
Japan
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Mouth Adult mouth,Cavital oralis,Cavitas oris,Cavum oris,Mouth cavity,Oral region,Oral vestibule,Regio oralis,Rima oris,Stoma,Stomatodaeum,Trophic apparatus,Vestibule of mouth,Vestibulum oris,Mouth,mouth
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Acetaldehyde Acetaldehyd,ACETALDEHYDE,Acetaldehyde,acetaldehyde,acetaldehydes,acetic aldehyde,Azetaldehyd,C2H4O,Ethanal,ethyl aldehyde
Group 0 name Corresponds to the control (unexposed) group for case-control studies
low acetaldehyde concentration group
Group 1 name Corresponds to the case (exposed) group for case-control studies
high acetaldehyde concentration group
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
The Sensor Gas Chromatograph SGEA-P2 (FIS Inc., Itami, Japan) was used to measure acetaldehyde concentrations in mouth air.
Group 0 sample size Number of subjects in the control (unexposed) group
6
Group 1 sample size Number of subjects in the case (exposed) group
6
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
current use

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V3-V4
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Statistical test
Mann-Whitney (Wilcoxon)
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No


Signature 1

Needs review

Curated date: 2021/01/10

Curator: Shaimaa Elsafoury

Revision editor(s): WikiWorks

Source: Figure 4

Description: Difference in relative abundance of tongue microbiome between High acetaldehyde concentration group and Low acetaldehyde concentration group.

Abundance in Group 1: increased abundance in high acetaldehyde concentration group

NCBI Quality ControlLinks
Gemella sanguinis
Veillonella parvula
Neisseria flavescens

Revision editor(s): WikiWorks

Signature 2

Needs review

Curated date: 2021/01/10

Curator: Shaimaa Elsafoury

Revision editor(s): WikiWorks

Source: Figure 4

Description: Difference in relative abundance of tongue microbiome between High acetaldehyde concentration group and Low acetaldehyde concentration group.

Abundance in Group 1: decreased abundance in high acetaldehyde concentration group

NCBI Quality ControlLinks
Streptococcus parasanguinis
Prevotella histicola

Revision editor(s): WikiWorks