Relationship between acetaldehyde concentration in mouth air and characteristics of microbiota of tongue dorsum in Japanese healthy adults: a cross-sectional study/Experiment 1
From BugSigDB
Subjects
- Location of subjects
- Japan
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Mouth Adult mouth,Cavital oralis,Cavitas oris,Cavum oris,Mouth cavity,Oral region,Oral vestibule,Regio oralis,Rima oris,Stoma,Stomatodaeum,Trophic apparatus,Vestibule of mouth,Vestibulum oris,Mouth,mouth
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Acetaldehyde Acetaldehyd,ACETALDEHYDE,Acetaldehyde,acetaldehyde,acetaldehydes,acetic aldehyde,Azetaldehyd,C2H4O,Ethanal,ethyl aldehyde
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- low acetaldehyde concentration group
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- high acetaldehyde concentration group
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- The Sensor Gas Chromatograph SGEA-P2 (FIS Inc., Itami, Japan) was used to measure acetaldehyde concentrations in mouth air.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 6
- Group 1 sample size Number of subjects in the case (exposed) group
- 6
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- current use
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Signature 1
Needs review
Source: Figure 4
Description: Difference in relative abundance of tongue microbiome between High acetaldehyde concentration group and Low acetaldehyde concentration group.
Abundance in Group 1: increased abundance in high acetaldehyde concentration group
| NCBI | Quality Control | Links |
|---|---|---|
| Gemella sanguinis | ||
| Veillonella parvula | ||
| Neisseria flavescens |
Revision editor(s): WikiWorks
Signature 2
Needs review
Source: Figure 4
Description: Difference in relative abundance of tongue microbiome between High acetaldehyde concentration group and Low acetaldehyde concentration group.
Abundance in Group 1: decreased abundance in high acetaldehyde concentration group
| NCBI | Quality Control | Links |
|---|---|---|
| Streptococcus parasanguinis | ||
| Prevotella histicola |
Revision editor(s): WikiWorks
