Differences in Gut Microbiota Profiles between Autoimmune Pancreatitis and Chronic Pancreatitis/Experiment 1

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Reviewed Marked as Reviewed by Claregrieve1 on 2022/09/1

Curated date: 2021/01/10

Curator: WikiWorks

Revision editor(s): Claregrieve1, WikiWorks

Subjects

Location of subjects
Japan
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Chronic pancreatitis chronic pancreatitis,Chronic pancreatitis (disorder),chronic pancreatitis (disorder) [Ambiguous],CP - Chronic pancreatitis,Pancreatitis, Chronic,pancreatitis, chronic,Pancreatitis, recurrent,Recurrent pancreatitis,Recurrent pancreatitis (disorder),Relapsing pancreatitis,Relapsing pancreatitis (disorder),Chronic pancreatitis
Group 0 name Corresponds to the control (unexposed) group for case-control studies
chronic pancreatitis
Group 1 name Corresponds to the case (exposed) group for case-control studies
autoimmune pancreatitis type 1
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
autoimmune pancreatitis type 1
Group 0 sample size Number of subjects in the control (unexposed) group
8
Group 1 sample size Number of subjects in the case (exposed) group
12

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V4-V5
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Statistical test
Fisher's Exact Test
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
No


Signature 1

Reviewed Marked as Reviewed by Claregrieve1 on 2022/09/1

Curated date: 2021/01/10

Curator: Rimsha Azhar

Revision editor(s): Claregrieve1, Atrayees, WikiWorks

Source: Figure 2, text

Description: Differential microbial abundance between patients with type 1 autoimmune pancreatitis (AIP) and chronic pancreatitis (CP)

Abundance in Group 1: decreased abundance in autoimmune pancreatitis type 1

NCBI Quality ControlLinks
Bacteroides ovatus
Clostridium lacusfryxellense
Enterocloster lavalensis
Streptococcus australis
Streptococcus gordonii
Anaerotignum lactatifermentans

Revision editor(s): Claregrieve1, Atrayees, WikiWorks