Gut microbiota is critical for the induction of chemotherapy-induced pain/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by ChiomaBlessing on 2024-2-22
Subjects
- Location of subjects
- United States of America
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Mus musculus
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Response to antibiotic Response to antibiotic,response to antibiotic
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- H2O mice
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Exposed abx mice
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Mice fed with antibiotic water
- Group 0 sample size Number of subjects in the control (unexposed) group
- 10
- Group 1 sample size Number of subjects in the case (exposed) group
- 10
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- None
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- RT-qPCR
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- ANOVA
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- decreased
Signature 1
Reviewed Marked as Reviewed by ChiomaBlessing on 2024-2-22
Source: Figure 1C
Description: Phylum analysis of altered microbiota in mice after antibiotic water feeding compared to mice fed with regular water
Abundance in Group 1: increased abundance in Exposed abx mice
| NCBI | Quality Control | Links |
|---|---|---|
| Cyanobacteriota | ||
| Pseudomonadota | ||
| Bacillota |
Revision editor(s): ChiomaBlessing
Signature 2
Reviewed Marked as Reviewed by ChiomaBlessing on 2024-2-22
Curated date: 2024/02/22
Curator: ChiomaBlessing
Revision editor(s): ChiomaBlessing, Scholastica, Joan Chuks
Source: Figure 1C
Description: Phylum analysis of altered microbiota in mice after antibiotic water feeding compared to mice fed with regular water
Abundance in Group 1: decreased abundance in Exposed abx mice
| NCBI | Quality Control | Links |
|---|---|---|
| Actinomycetota | ||
| Bacteroidota | ||
| Fusobacteriia | ||
| Mycoplasmatota | ||
| Verrucomicrobiia | ||
| Candidatus Saccharibacteria |
Revision editor(s): ChiomaBlessing, Scholastica, Joan Chuks
