Intestinal microbiota development in preterm neonates and effect of perinatal antibiotics/Experiment 7
From BugSigDB
Reviewed Marked as Reviewed by Atrayees on 2023-7-21
Subjects
- Location of subjects
- Spain
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Antimicrobial agent antibiotic,antibiotics,Antibiotika,Antibiotikum,antibiotique,antimicrobial,antimicrobial agents,microbicide,microbicides,Antimicrobial agent,antimicrobial agent
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- 30-day old full-term neonates not exposed to antibiotics (IAP/postnatal)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- 30-day old pre-tem neonates exposed to antibiotics (IAP)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- antenatal/postnatal antibiotic exposure
- Group 0 sample size Number of subjects in the control (unexposed) group
- 14
- Group 1 sample size Number of subjects in the case (exposed) group
- 10
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V4
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Ion Torrent
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- ANOVA
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Signature 1
Reviewed Marked as Reviewed by Atrayees on 2023-7-21
Curated date: 2021/01/10
Curator: Mst Afroza Parvin
Revision editor(s): WikiWorks, Atrayees, ChiomaBlessing
Source: Results within text under the subheading "Impact of Delivery Mode and Antibiotics Use on the Establishment of Intestinal Microbiota" (2nd paragraph, from line 18)
Description: Impact of Antibiotics Use on the Intestinal Microbiota between 30-day old full-term neonates not exposed to antibiotics (IAP/postnatal) and 30-day old pre-term neonates exposed to antibiotics (IAP)
Abundance in Group 1: decreased abundance in 30-day old pre-tem neonates exposed to antibiotics (IAP)
| NCBI | Quality Control | Links |
|---|---|---|
| Comamonadaceae | ||
| Staphylococcaceae | ||
| unclassified Bacilli |
Revision editor(s): WikiWorks, Atrayees, ChiomaBlessing
