Modulation of potential respiratory pathogens by pH1N1 viral infection/Experiment 1
Curated date: 2021/06/09
Curator: Claregrieve1
Revision editor(s): WikiWorks, LGeistlinger, Fatima, Claregrieve1, Peace Sandy
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Throat Gula,Throat,throat
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Influenza A (H1N1) Influenza A (H1N1),influenza A (H1N1)
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Pneumonia patients without any influenza A infection
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Pneumonia patients with pH1N1 infection
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Positive lab test (real-time PCR or cell culture) and criteria for pneumonia simultaneously met, with pH1N1 infection
- Group 0 sample size Number of subjects in the control (unexposed) group
- 11
- Group 1 sample size Number of subjects in the case (exposed) group
- 11
Lab analysis
- Sequencing type
- WMS
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- raw counts
- Statistical test
- DESeq2
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
Signature 1
Source: Figure 1a-c
Description: Relative microbial abundance of pH1N1-infected and uninfected pneumonia patients
Abundance in Group 1: increased abundance in Pneumonia patients with pH1N1 infection
| NCBI | Quality Control | Links |
|---|---|---|
| Bacillota | ||
| Pseudomonadota | ||
| Bacillaceae | ||
| Moraxellaceae | ||
| Pseudomonadaceae | ||
| Acinetobacter | ||
| Pseudomonas | ||
| Bacillus |
Revision editor(s): Claregrieve1
Signature 2
Source: Figure 1a-c
Description: Relative microbial abundance of pH1N1-infected and uninfected pneumonia patients
Abundance in Group 1: decreased abundance in Pneumonia patients with pH1N1 infection
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroidota | ||
| Prevotellaceae | ||
| Veillonellaceae | ||
| Neisseriaceae | ||
| Neisseria | ||
| Prevotella | ||
| Veillonella |
Revision editor(s): Claregrieve1
Signature 3
Source: Figure 1b
Description: Relative microbial abundance of pH1N1-infected and uninfected pneumonia patients at the family level
Abundance in Group 1: increased abundance in Pneumonia patients with pH1N1 infection
| NCBI | Quality Control | Links |
|---|---|---|
| Bacillaceae | ||
| Moraxellaceae | ||
| Pseudomonadaceae |
Revision editor(s): Claregrieve1
Signature 4
Source: Figure 1b
Description: Relative microbial abundance of pH1N1-infected and uninfected pneumonia patients at the family level
Abundance in Group 1: decreased abundance in Pneumonia patients with pH1N1 infection
| NCBI | Quality Control | Links |
|---|---|---|
| Neisseriaceae | ||
| Prevotellaceae | ||
| Veillonellaceae |
Revision editor(s): Claregrieve1
Signature 5
Source: Figure 1c
Description: Relative microbial abundance of pH1N1-infected and uninfected pneumonia patients at the genus level
Abundance in Group 1: increased abundance in Pneumonia patients with pH1N1 infection
| NCBI | Quality Control | Links |
|---|---|---|
| Acinetobacter | ||
| Bacillus | ||
| Pseudomonas |
Revision editor(s): Claregrieve1
Signature 6
Source: Figure 1c
Description: Relative microbial abundance of pH1N1-infected and uninfected pneumonia patients at the genus level
Abundance in Group 1: decreased abundance in Pneumonia patients with pH1N1 infection
| NCBI | Quality Control | Links |
|---|---|---|
| Neisseria | ||
| Prevotella | ||
| Veillonella |
Revision editor(s): Claregrieve1
