Joint effects of pregnancy, sociocultural, and environmental factors on early life gut microbiome structure and diversity/Experiment 1/Signature 1
Source: FIGURE 5 , FIGURE 6
Description: Top genera are significantly associated with each factor retained in multi-factor neonatal gut microbiome composition models. For plotting purposes, “top” genera for each factor were defined using two characteristics: (1) the number of taxa significantly associated with it (to avoid spurious findings) and (2) how “discriminatory” the genera was, defined by consistency in the direction of taxa-specific associations. Each factor displays up to the top ten genera that best discriminated each factor, given the genera had at least 5 significant taxa. Abbreviations: ETS, environmental tobacco smoke; NSV, neonatal study visit at 1-month of age.
Top genera significantly associated with each factor retained in multi-factor models of infant gut microbiome composition. For plotting purposes, “top” genera for each factor were defined using two characteristics: (1) the number of taxa significantly associated with it (to avoid spurious findings) and (2) how “discriminatory” the genera was, defined by consistency in the direction of taxa-specific associations. Each factor displays up to the top ten genera that best discriminated each factor, given the genera had at least 5 significant taxa. Abbreviations: BMI, body mass index; ISV, infant study visit at 6-months of age.
Abundance in Group 1: increased abundance in Infants (median age = 6.6 months)
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