Effect of ethnicity and socioeconomic variation to the gut microbiota composition among pre-adolescent in Malaysia/Experiment 3
From BugSigDB
Reviewed Marked as Reviewed by Folakunmi on 2024-2-17
Subjects
- Location of subjects
- Malaysia
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Socioeconomic status class,Socioeconomic status,socioeconomic status,socioeconomic factors
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Malays children (Moderate SES, household income =>RM500)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Orang Asli children (low SES, household income <RM500)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Gut microbiota from fecal samples of 20 Orang Asli children whose household income<RM500. 45% of the households earn < RM500 Note: Poverty line = RM 764($254).
- Group 0 sample size Number of subjects in the control (unexposed) group
- 24
- Group 1 sample size Number of subjects in the case (exposed) group
- 20
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- unspecified
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V3-V5
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- PERMANOVA
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- .05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- Yes
Alpha Diversity
- Pielou Quantifies how equal the community is numerically
- increased
- Shannon Estimator of species richness and species evenness: more weight on species richness
- increased
- Simpson Estimator of species richness and species evenness: more weight on species evenness
- increased
- Inverse Simpson Modification of Simpsons index D as 1/D to obtain high values in datasets of high diversity and vice versa
- increased
Signature 1
Reviewed Marked as Reviewed by Claregrieve1 on 2022/11/7
Source: Table 3
Description: Differential microbial abundance between Malay and Orang Asli children.
Abundance in Group 1: increased abundance in Orang Asli children (low SES, household income <RM500)
| NCBI | Quality Control | Links |
|---|---|---|
| Aeromonadales | ||
| Spirochaetota | ||
| unclassified Bacteria | ||
| unclassified Bacteroidota | ||
| unclassified Clostridia | ||
| unclassified Deltaproteobacteria | ||
| unclassified Oscillospiraceae |
Revision editor(s): Kaluifeanyi101, Claregrieve1
Signature 2
Reviewed Marked as Reviewed by Claregrieve1 on 2022/11/7
Source: Table 3
Description: Differential microbial abundance between Malay and Orang Asli children.
Abundance in Group 1: decreased abundance in Orang Asli children (low SES, household income <RM500)
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroidales | ||
| Selenomonadales |
Revision editor(s): Kaluifeanyi101, Claregrieve1
